Tsuchiya A, Suzuki S, Nomizu T, Yamaki Y, Abe R, Katayama S
Second Department of Surgery, Fukushima Medical College, Japan.
Jpn J Surg. 1990 May;20(3):341-5. doi: 10.1007/BF02470671.
Three cases of squamous cell carcinoma of the thyroid are reported herein. In all cases, the carcinoma occurred in old age and was characterized by a rapidly growing tumor, usually associated with dyspnea and dysphagia. The prognosis of all 3 cases was poor, with a mean survival of only 6.3 months. Although squamous metaplasia is an accepted etiology of this disease, clinical investigation of the cases presented here does not favor it in consideration of the clinical features of papillary carcinoma of the thyroid with squamous metaplasia. The histological findings of our cases revealed areas of cystic formation, suggesting that some of these carcinomas may be derived from remnants of embryonic origin.
本文报告了3例甲状腺鳞状细胞癌。所有病例中，癌均发生于老年，其特征为肿瘤生长迅速，通常伴有呼吸困难和吞咽困难。所有3例的预后均较差，平均生存期仅6.3个月。尽管鳞状化生是该疾病公认的病因，但考虑到伴有鳞状化生的甲状腺乳头状癌的临床特征，本文所呈现病例的临床研究并不支持这一观点。我们病例的组织学检查结果显示有囊性形成区域，提示其中一些癌可能起源于胚胎残留组织。
