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Two additional cases of t dic(9:12) in acute lymphocytic leukemia (ALL): prognosis in ALL with dic(9:12).

作者信息

Huret J L, Heerema N A, Brizard A, Provisor A J, Benz-Lemoine E, Guilhot F, Savage J R, Tanzer J

机构信息

Département d'Hématologie et Oncologie Médicale, CNRS URA 1338, Hôpital Jean Bernard, Poitiers, France.

出版信息

Leukemia. 1990 Jun;4(6):423-5.

PMID:2193203
Abstract

We report two occurrences of dic(9;12) in acute lymphoblastic leukemia and review previous cases. Cases of dic(9;12) share common features with cases of 9p and 12p rearrangements, but prognosis seems particularly good in cases of dic(9;12). The persistence of a specific dicentric in stable clones is remarkable and points to unusual centromeric behavior and/or marked selective advantage of the anomaly.

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