Cardiology Department, Patras University Hospital, Patras, Greece.
Clin Cardiol. 2011 Oct;34(10):588-92. doi: 10.1002/clc.20929. Epub 2011 Sep 19.
The extensive use of stents during percutaneous coronary intervention (PCI) is associated with concerns about their potential adverse effects. In-stent restenosis and stent thrombosis definitely significantly affect the PCI outcome. However, review of recent relevant studies suggests that stent-related problems may have been somewhat overestimated when compared to coronary artery disease (CAD) progression at nonstented coronary segments as causative factors of adverse cardiac clinical events late (>30 days) post-PCI. Both stent-related problems and native CAD progression have to be equally addressed to optimize the PCI clinical benefit.
经皮冠状动脉介入治疗 (PCI) 中广泛使用支架引起了对其潜在不良影响的关注。支架内再狭窄和支架内血栓形成肯定会显著影响 PCI 的结果。然而,最近相关研究的综述表明,与非支架置入冠状动脉节段的冠状动脉疾病 (CAD) 进展相比,支架相关问题可能被高估为 PCI 后晚期 (>30 天) 不良心脏临床事件的原因。为了优化 PCI 的临床获益,必须同等解决支架相关问题和原发性 CAD 进展。