Alajbeg Ivan, Rogulj Ana Andabak, Hutinec Zdenka
Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Croatia.
Acta Dermatovenerol Croat. 2011;19(3):165-9.
Orofacial granulomatosis (OFG) is an uncommon disease, usually presenting as recurrent or persistent swelling of the soft tissues in the orofacial region, predominantly lips (cheilitis granulomatosa). The cause of this illness is unknown. OFG may also be part of the triad of Melkersson-Rosenthal syndrome (MRS) and some consider it a monosymptomatic form of MRS. We describe a case of a Croatian male patient with recurrent swelling limited to the upper lip for the past 6 years. After establishing the diagnosis, we performed intralesional triamcinolone injections (16 mg, twice on a weekly schedule), resulting in complete remission. OFG differential diagnosis and treatment modalities are discussed.
口面部肉芽肿病（OFG）是一种罕见疾病，通常表现为口面部区域软组织反复或持续肿胀，主要累及唇部（肉芽肿性唇炎）。该病病因不明。OFG也可能是梅尔克森 - 罗森塔尔综合征（MRS）三联征的一部分，有些人认为它是MRS的单症状形式。我们描述了一例克罗地亚男性患者，在过去6年中反复出现仅局限于上唇的肿胀。确诊后，我们进行了病灶内注射曲安奈德（16毫克，每周两次），结果实现了完全缓解。本文讨论了OFG的鉴别诊断和治疗方式。
