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全髋关节置换术后围手术期神经损伤:20 年队列研究中的区域麻醉风险。

Perioperative nerve injury after total hip arthroplasty: regional anesthesia risk during a 20-year cohort study.

机构信息

Department of Anesthesiology, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.

出版信息

Anesthesiology. 2011 Dec;115(6):1172-8. doi: 10.1097/ALN.0b013e3182326c20.

Abstract

BACKGROUND

Perioperative nerve injury (PNI) is a recognized complication of total hip arthroplasty (THA). Regional anesthesia (RA) techniques may increase the risk of neurologic injury. Using a retrospective cohort study, the authors tested the hypothesis that use of RA increases the risk for PNI after elective THA.

METHODS

All adult patients who underwent elective THA at Mayo Clinic during a 20-yr period were included. The primary outcome was the presence of a new PNI within 3 months of surgery. Multivariable logistic regression was used to evaluate patient, surgical, and anesthetic risk factors for PNI.

RESULTS

Of 12,998 patients undergoing THA, 93 experienced PNI (incidence = 0.72%; 95% CI 0.58-0.88%). PNI was not associated with type of anesthesia (OR = 0.72 for neuraxial-combined vs. general; 95% CI 0.46-1.14) or peripheral nerve blockade (OR = 0.65; 95% CI 0.34-1.21). The risk for PNI was associated with younger age (OR = 0.79 per 10-yr increase; 95% CI 0.69-0.90), female gender (OR = 1.72; 95% CI 1.12-2.64), longer operations (OR = 1.10 per 30-min increase; 95% CI 1.03-1.18) or posterior surgical approach (OR = 1.91 vs. anterior approach; 95% CI 1.22-2.99). Neurologic recovery was not influenced by the use of RA techniques in patients with PNI.

CONCLUSIONS

The risk for PNI after THA was not increased with the use of neuraxial anesthesia or peripheral nerve blockade. Neurologic recovery in patients who experienced PNI was not affected by the use of RA. These results support the use of RA techniques in patients undergoing elective THA given their known functional and clinical benefits.

摘要

背景

围手术期神经损伤(PNI)是全髋关节置换术(THA)的一种公认的并发症。区域麻醉(RA)技术可能会增加神经损伤的风险。作者使用回顾性队列研究检验了假设,即选择性 THA 中使用 RA 会增加 PNI 的风险。

方法

所有在 20 年期间在梅奥诊所接受选择性 THA 的成年患者均被纳入研究。主要结局是手术 3 个月内是否存在新的 PNI。多变量逻辑回归用于评估患者、手术和麻醉相关的 PNI 危险因素。

结果

在 12998 例接受 THA 的患者中,93 例发生 PNI(发生率=0.72%;95%CI 0.58-0.88%)。PNI 与麻醉类型无关(神经轴联合麻醉与全身麻醉的比值比=0.72;95%CI 0.46-1.14)或周围神经阻滞(比值比=0.65;95%CI 0.34-1.21)。PNI 的风险与年龄较小(每增加 10 岁,比值比=0.79;95%CI 0.69-0.90)、女性(比值比=1.72;95%CI 1.12-2.64)、手术时间较长(每增加 30 分钟,比值比=1.10;95%CI 1.03-1.18)或后路手术入路(比值比=1.91 比前路;95%CI 1.22-2.99)相关。在发生 PNI 的患者中,RA 技术的使用并未影响神经恢复。

结论

THA 后发生 PNI 的风险并未因使用神经轴麻醉或周围神经阻滞而增加。在发生 PNI 的患者中,RA 的使用并未影响神经恢复。这些结果支持在接受选择性 THA 的患者中使用 RA 技术,因为它们具有已知的功能和临床益处。

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