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使用纽约州数据库(全州规划和研究合作系统)对 207,000 例全髋关节置换术后周围神经损伤的危险因素分析。

Risk Factors for Peripheral Nerve Injury After 207,000 Total Hip Arthroplasties Using a New York State Database (Statewide Planning and Research Cooperative System).

机构信息

Division of Adult Reconstruction and Joint Replacement, Hospital for Special Surgery, New York, NY.

Healthcare Research Institute, Hospital for Special Surgery, New York, NY.

出版信息

J Arthroplasty. 2019 Aug;34(8):1787-1792. doi: 10.1016/j.arth.2019.03.043. Epub 2019 Mar 28.

Abstract

BACKGROUND

Peripheral nerve injury (PNI) is a devastating complication following total hip arthroplasty (THA). The purpose of this study was to identify risk factors for PNI after THA using a New York Statewide Planning and Research Cooperative System (SPARCS).

METHODS

The SPARCS database was queried to identify patients who had undergone THA from 1996 to 2011. Patient demographics, medical history, surgical details, hospital characteristics, and in-hospital complications were recorded. Cases in which a new unilateral PNI was identified were compiled, as were control cases in which a new PNI did not occur. The characteristics of cases and controls underwent univariate testing and a multivariate logistic regression using Akaike information criterion model selection to identify risk factors for the development of PNI after THA.

RESULTS

207,981 cases were identified, and 487 were coded as having a new PNI. Preexisting spinal conditions (odds ratio [OR] = 2.55, confidence interval [CI] = 1.61-3.83) were strongly correlated with the development of PNI postoperatively, as was dislocation (OR = 2.58, CI = 1.01-5.30) and diabetes with chronic complications (OR = 2.26, CI = 0.96-4.43). Younger age, in-hospital complications, and thromboembolic events were also associated with postoperative PNI.

CONCLUSION

The incidence of PNI after THA was consistent with previous large-scale studies but may under-represent the true incidence because of undercoding inherent in large database studies. Previous spine disorder, chronic diabetes, younger age, and in-hospital postoperative complications all increased the risk of PNI. This study can help health-care providers and systems identify patients at higher risk of this serious complication.

摘要

背景

周围神经损伤(PNI)是全髋关节置换术(THA)后的一种毁灭性并发症。本研究旨在使用纽约州规划与研究合作系统(SPARCS)确定 THA 后 PNI 的危险因素。

方法

查询 SPARCS 数据库,以确定 1996 年至 2011 年间接受 THA 的患者。记录患者的人口统计学、病史、手术细节、医院特征和住院并发症。编译了新单侧 PNI 病例和未发生新 PNI 的对照病例。对病例和对照的特征进行单变量检验和基于 Akaike 信息准则模型选择的多变量逻辑回归,以确定 THA 后 PNI 发展的危险因素。

结果

确定了 207981 例病例,其中 487 例被编码为出现新的 PNI。术前脊柱疾病(比值比 [OR] = 2.55,置信区间 [CI] = 1.61-3.83)与术后 PNI 的发生密切相关,脱位(OR = 2.58,CI = 1.01-5.30)和糖尿病伴慢性并发症(OR = 2.26,CI = 0.96-4.43)也是如此。年龄较小、住院并发症和血栓栓塞事件也与术后 PNI 相关。

结论

THA 后 PNI 的发生率与之前的大规模研究一致,但由于大型数据库研究中固有的编码不足,可能低估了真实发生率。先前的脊柱疾病、慢性糖尿病、年龄较小和术后住院并发症均增加了 PNI 的风险。本研究可以帮助医疗保健提供者和系统识别出发生这种严重并发症风险较高的患者。

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