Vanacker B, Van Aken H
Department of Anesthesiology, University Hospitals, Katholieke Universiteit Leuven, Belgium.
Acta Anaesthesiol Belg. 1990;41(1):9-12.
Increases in blood pressure and heart rate often seen with laryngoscopy and endotracheal intubation during induction of anesthesia can be dangerous for many patients. In twenty five patients pretreated with ketanserin, a new antihypertensive agent, changes in blood pressure and heart rate were compared with the hemodynamic parameters of twenty untreated patients. Ketanserin 10 mg intravenously was administered prior to induction of anesthesia. Ten mg i.v. ketanserin will not prevent increases in arterial pressure; however the increases in diastolic and mean arterial pressure are significantly lower than these increases in untreated patients.
麻醉诱导期间喉镜检查和气管插管时常见的血压和心率升高对许多患者可能是危险的。在25例预先使用新型抗高血压药物酮色林治疗的患者中，将血压和心率变化与20例未治疗患者的血流动力学参数进行了比较。麻醉诱导前静脉注射10毫克酮色林。静脉注射10毫克酮色林不能预防动脉压升高；然而，舒张压和平均动脉压的升高明显低于未治疗患者的升高幅度。
