Noirclerc M J, Metras D, Vaillant A, Dumon J F, Zimmermann J M, Caamano A, Orsoni P C
Department of Thoracic Surgery, Hôpital Salvator, Marseille, France.
Eur J Cardiothorac Surg. 1990;4(6):314-7. doi: 10.1016/1010-7940(90)90208-h.
During heart-lung or double lung transplantation, the airway anastomosis is usually made at the tracheal level. Healing of this anastomosis is one source of postoperative complications especially after double lung transplantation (DLT). In this series of 10 patients with cystic fibrosis undergoing DLT, the tracheas of donor and recipient were anastomosed with omental wrapping in 2 cases while the two main stem bronchi were joined without omental wrapping in 8. Endoscopy disclosed no sign of ischaemia in the patients with bilateral bronchial anastomoses. Three patients died on day 20, 21 and 35, respectively, after DLT. Two of these patients (one with a tracheal and the other with bronchial anastomoses) showed no complication at the level of the suture line. The third patient (with bronchial suture) suffered dehiscence of both anastomoses which was attributed to a misdosage of corticosteroids. Of the 6 patients alive after bronchial anastomosis, 3 recovered uneventfully and 3 who had required prolonged postoperative mechanical ventilation developed bronchomalacia. Bronchomalacia was treated by laser resection and stenting. Dehiscence did not occur in any of these six cases. This technique was based on the findings of 12 fresh cadaver dissections showing that collaterals between the bronchial arteries and the pulmonary arteries and veins extend up to the origin of the main stem bronchus. Bronchial suture without omental wrap may be used for double lung and heart-lung transplantation instead of tracheal suture.
在心肺或双肺移植过程中,气道吻合通常在气管水平进行。这种吻合口的愈合是术后并发症的一个来源,尤其是在双肺移植(DLT)后。在这组接受DLT的10例囊性纤维化患者中,2例供体和受体的气管采用网膜包裹吻合,8例主支气管吻合时未采用网膜包裹。内镜检查显示双侧支气管吻合的患者没有缺血迹象。3例患者分别在DLT后第20、21和35天死亡。其中2例患者(1例为气管吻合,另1例为支气管吻合)在缝线处未出现并发症。第3例患者(支气管缝合)出现两处吻合口裂开,这归因于皮质类固醇剂量错误。在支气管吻合术后存活的6例患者中,3例恢复顺利,3例术后需要长时间机械通气的患者出现了支气管软化。支气管软化通过激光切除和支架置入进行治疗。这6例患者均未发生裂开。该技术基于12例新鲜尸体解剖的结果,结果显示支气管动脉与肺动脉和静脉之间的侧支延伸至主支气管起始处。双肺和心肺移植可采用无网膜包裹的支气管缝合代替气管缝合。