School of Surgery, The University of Western Australia, Nedlands, Australia.
Int J Audiol. 2011 Dec;50(12):881-6. doi: 10.3109/14992027.2011.606286. Epub 2011 Sep 21.
In this study, we aimed to explore a variation of the NTT standard protocol that would be more beneficial for those patients with hearing loss >50 dB HL in the worst ear (average hearing thresholds at 0.5, 1, 2, and 4 KHz).
This study involved 26 subjects who had previously undergone NTT at a single private practice.
Patients with high level of hearing loss were divided into two groups: Standard protocol group (SP) concluded the treatment following the standard NTT protocol proposed by the treatment's developers and Neuromonics guidelines. Extended protocol group (EP) was treated using a variation of the standard protocol, in which patients continued in stage 1 of the treatment for a prolonged time. Consistent with previously reported studies of the NTT, the tinnitus reaction questionnaire was used to assess tinnitus distress. Clinical outcomes for the two groups were analysed.
Both groups achieved statistically significant improvement of their tinnitus distress. EP group achieved quicker clinical benefits when compared to the SP group.
Extension of high stimulation period from two to four months may be beneficial for patients with higher level of hearing loss undergoing NTT.
本研究旨在探索一种 NTT 标准方案的变体,该方案将更有益于那些最差耳听力损失 >50dBHL(0.5、1、2 和 4kHz 平均听阈)的患者。
本研究纳入了 26 名曾在一家私人诊所接受过 NTT 的患者。
将高听力损失水平的患者分为两组:标准方案组(SP)按照治疗开发者提出的 NTT 标准方案和 Neuromonics 指南进行治疗。扩展方案组(EP)采用标准方案的变体进行治疗,患者在治疗的第一阶段延长治疗时间。与之前报道的 NTT 研究一致,使用耳鸣反应问卷评估耳鸣困扰。分析两组的临床结果。
两组的耳鸣困扰均有统计学显著改善。与 SP 组相比,EP 组更快地获得了临床获益。
对于接受 NTT 的较高听力损失水平的患者,将高刺激期从两个月延长至四个月可能有益。