ENT Department, Robert Debré Hospital, Paris, France.
Int J Audiol. 2012 Apr;51(4):282-6. doi: 10.3109/14992027.2011.601469. Epub 2011 Sep 22.
To evaluate the feasibility, the duration and results of sedation by intrarectal pentobarbital and oral alimemazine for auditory brain stem responses (ABR) and auditory steady-state responses (ASSR) recordings in children aged 2 to 5 years.
Prospective study.
180 consecutive children aged 2 to 5 years, referred for language retardation and/or behavioral problems, who could not be tested by behavioral methods, underwent ABR and ASSR recordings. The children who did not spontaneously nap were sedated by intrarectal pentobarbital eventually potentiated by oral alimemazine.
A spontaneous nap was obtained in only 23 cases, 72 children received only pentobarbital, and 85 received both pentobarbital and alimemazine. Even so, recording was impossible in 16 cases, and interrupted before completion of the ASSR recordings in 45 cases. Children went to sleep in average 64 min +/- 40. The average recording time for the ABR was 20 minutes, and for the ASSR 25 minutes.
Sedation by pentobarbital, eventually completed by oral alimemazine, allows ABR and/or ASSR recordings in 89.8% of the children who did not nap in the recording room, and is therefore a good alternative to general anesthesia in these children.
评估直肠内戊巴比妥钠和口服阿利美嗪镇静用于 2 至 5 岁儿童听觉脑干反应(ABR)和听觉稳态反应(ASSR)记录的可行性、持续时间和结果。
前瞻性研究。
180 例连续就诊的 2 至 5 岁儿童,因语言发育迟缓或行为问题就诊,无法通过行为方法进行测试,进行 ABR 和 ASSR 记录。未自发午睡的儿童接受直肠内戊巴比妥钠镇静,最终用口服阿利美嗪增强。
仅 23 例儿童自发午睡,72 例儿童仅接受戊巴比妥钠,85 例儿童同时接受戊巴比妥钠和阿利美嗪。即便如此,仍有 16 例记录失败,45 例 ASSR 记录中断。儿童平均在 64 分钟 +/- 40 分钟入睡。ABR 的平均记录时间为 20 分钟,ASSR 为 25 分钟。
戊巴比妥钠镇静,最终用口服阿利美嗪完成,使 89.8%未在录音室午睡的儿童能够进行 ABR 和/或 ASSR 记录,因此是这些儿童全麻的良好替代方法。