Department of Radiology and Research, University of Ulsan College of Medicine, Songpa-gu, Seoul, Republic of Korea.
J Vasc Interv Radiol. 2011 Dec;22(12):1727-32. doi: 10.1016/j.jvir.2011.08.012. Epub 2011 Sep 19.
To compare retrospectively clinical outcomes in patients who underwent metallic stent placement for colonic obstruction caused by colonic or extracolonic malignancies.
Palliative stent placement was performed for inoperable malignant colonic obstruction in 108 patients, including 58 for primary colorectal cancer and 50 for extracolonic malignancies including gastric (n = 31), pancreatic (n = 8), ovarian (n = 4), bladder (n = 2), bile duct (n = 1), gallbladder (n = 1), breast (n = 1), esophageal (n = 1), and renal (n = 1) cancers.
Technical (84% vs 94%, P = .137) and clinical (98% vs 96%, P = .533) success rates of stent placement were similar in patients with primary colorectal cancer and patients with extracolonic malignancies. Rates of perforation, stent migration, tumor overgrowth, bleeding, and pain did not differ significantly between groups of patients with primary colorectal cancer and extracolonic malignancies. The median symptom-free survival periods were 4 months in patients with primary colorectal cancer and 3 months in patients with extracolonic malignancies (P = .072).
Metallic stent placement was clinically effective in the palliative treatment of colonic obstructions in patients with primary colorectal cancer and patients with extracolonic malignancies.
回顾性比较因结直肠或结外恶性肿瘤引起的结肠梗阻患者行金属支架置入的临床疗效。
108 例不能手术的恶性结肠梗阻患者接受了姑息性支架置入术，其中 58 例为原发性结直肠癌，50 例为结外恶性肿瘤，包括胃（n = 31）、胰腺（n = 8）、卵巢（n = 4）、膀胱（n = 2）、胆管（n = 1）、胆囊（n = 1）、乳腺（n = 1）、食管（n = 1）和肾（n = 1）癌。
原发性结直肠癌患者和结外恶性肿瘤患者支架置入的技术（84%比 94%，P =.137）和临床（98%比 96%，P =.533）成功率相似。穿孔、支架迁移、肿瘤过度生长、出血和疼痛的发生率在原发性结直肠癌患者和结外恶性肿瘤患者之间无显著差异。原发性结直肠癌患者的中位无症状生存时间为 4 个月，结外恶性肿瘤患者为 3 个月（P =.072）。
金属支架置入术在原发性结直肠癌和结外恶性肿瘤患者的结肠梗阻姑息治疗中具有临床疗效。
