Rothfield R E, Johnson J T, Stavrides A
Department of Otolaryngology, University of Pittsburgh School of Medicine, PA 15213.
Head Neck. 1990 Jul-Aug;12(4):352-4. doi: 10.1002/hed.2880120414.
Primary extramedullary plasmacytoma (PEMP) is a tumor of atypical neoplastic cells that arise outside the bone marrow in patients without clinical evidence of existing multiple myeloma. These rare tumors, which can occur in virtually any part of the body, have shown a clear predilection for the head and neck. Yet despite the fact that nearly 80% of these tumors can be found in the upper respiratory tract or oral cavity, their involvement in the parotid is singularly rare. The clinical behavior of this tumor is not yet well-defined, and local recurrence, distant metastasis, and transformation to multiple myeloma have all been reported. Since the first case of parotid PEMP was reported in 1965, 8 additional cases have been noted in the literature. This is the 9th case of PEMP of the parotid to be described.
原发性髓外浆细胞瘤（PEMP）是一种由非典型肿瘤细胞构成的肿瘤，发生于无多发性骨髓瘤临床证据患者的骨髓外。这些罕见肿瘤几乎可发生于身体的任何部位，明显好发于头颈部。然而，尽管近80%的此类肿瘤可在上呼吸道或口腔发现，但累及腮腺的情况极为罕见。该肿瘤的临床行为尚未明确界定，已有局部复发、远处转移及转化为多发性骨髓瘤的报道。自1965年首例腮腺PEMP报道以来，文献中又记载了8例。本文描述的是第9例腮腺PEMP。
