Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.
作者信息
Blaho Victoria A, Hla Timothy
机构信息
Center for Vascular Biology, Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York 10065, USA.
出版信息
Chem Rev. 2011 Oct 12;111(10):6299-320. doi: 10.1021/cr200273u. Epub 2011 Sep 22.
Abstract
摘要
相似文献
1
Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.鞘氨醇-1-磷酸和溶血磷脂酸受体对哺乳动物生理、发育及疾病的调节作用
Chem Rev. 2011 Oct 12;111(10):6299-320. doi: 10.1021/cr200273u. Epub 2011 Sep 22.
2
A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay.一种使用单克隆抗体和动力学排除分析法测量鞘氨醇-1-磷酸和溶血磷脂酸与载体蛋白结合的新方法。
J Lipid Res. 2016 Sep;57(9):1737-47. doi: 10.1194/jlr.D068866. Epub 2016 Jul 21.
3
Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function.鞘氨醇-1-磷酸裂解酶，鞘氨醇-1-磷酸信号传导和功能的关键调节因子。
Adv Enzyme Regul. 2010;50(1):349-62. doi: 10.1016/j.advenzreg.2009.10.024. Epub 2009 Nov 13.
4
[Cardiovascular function of sphingosine 1-phosphate signaling].
Seikagaku. 2011 Jun;83(6):536-44.
5
Of spiders and crabs: the emergence of lysophospholipids and their metabolic pathways as targets for therapy in cancer.蜘蛛与螃蟹：溶血磷脂及其代谢途径作为癌症治疗靶点的出现
Clin Cancer Res. 2006 Nov 15;12(22):6598-602. doi: 10.1158/1078-0432.CCR-06-1721.
6
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins.溶血磷脂酸受体1与不同G蛋白相互作用的结构解析。
J Struct Biol. 2025 Mar;217(1):108164. doi: 10.1016/j.jsb.2024.108164. Epub 2024 Dec 24.
7
Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.溶血磷脂代谢物溶血磷脂酸和 1-磷酸鞘氨醇在肺纤维化中的作用。
Proc Am Thorac Soc. 2012 Jul;9(3):102-10. doi: 10.1513/pats.201201-005AW.
8
New aspects of sphingosine 1-phosphate signaling in mammalian cells.哺乳动物细胞中1-磷酸鞘氨醇信号传导的新进展。
Adv Enzyme Regul. 2009;49(1):214-21. doi: 10.1016/j.advenzreg.2009.01.011.
9
The critical micelle concentrations of lysophosphatidic acid and sphingosylphosphorylcholine.
Chem Phys Lipids. 2004 Jul;130(2):197-201. doi: 10.1016/j.chemphyslip.2004.03.001.
10
Identification of the orphan GPCR, P2Y(10) receptor as the sphingosine-1-phosphate and lysophosphatidic acid receptor.鉴定孤儿G蛋白偶联受体P2Y(10)受体为1-磷酸鞘氨醇和溶血磷脂酸受体。
Biochem Biophys Res Commun. 2008 Jul 11;371(4):707-12. doi: 10.1016/j.bbrc.2008.04.145. Epub 2008 May 6.
引用本文的文献
1
Chloride intracellular channel (CLIC) protein function in S1P-induced Rac1 activation requires membrane localization of the C-terminus, but not thiol-transferase nor ion channel activities.氯离子细胞内通道（CLIC）蛋白在S1P诱导的Rac1激活中的功能需要C末端的膜定位，但不需要硫醇转移酶活性或离子通道活性。
Front Cell Dev Biol. 2025 Apr 1;13:1565262. doi: 10.3389/fcell.2025.1565262. eCollection 2025.
2
Interrogating mediators of single-cell transcriptional changes in the acute damaged cerebral cortex: Insights into endothelial-astrocyte interactions.探究急性损伤大脑皮层单细胞转录变化的介导因子：对内皮细胞-星形胶质细胞相互作用的见解
Mol Cell Neurosci. 2025 Jun;133:104003. doi: 10.1016/j.mcn.2025.104003. Epub 2025 Mar 14.
3
Chloride intracellular channel (CLIC) protein function in S1P-induced Rac1 activation requires membrane localization of the C-terminus, but not thiol-transferase nor ion channel activities.氯离子细胞内通道（CLIC）蛋白在S1P诱导的Rac1激活中的功能需要C末端的膜定位，但不需要硫醇转移酶或离子通道活性。
bioRxiv. 2025 Jan 24:2025.01.22.634370. doi: 10.1101/2025.01.22.634370.
4
Synthesis and evaluation of 6-arylaminobenzamides as positron emission tomography imaging ligands for the sphingosine-1-phosphate-5 receptor.6-芳基氨基苯甲酰胺作为鞘氨醇-1-磷酸-5受体正电子发射断层显像配体的合成与评价
RSC Med Chem. 2025 Jan 3;16(3):1235-1249. doi: 10.1039/d4md00929k. eCollection 2025 Mar 19.
5
Research Hotspots and Trends in Global Cancer immunometabolism:A Bibliometric Analysis from 2000 to 2023.全球癌症免疫代谢的研究热点与趋势：2000年至2023年的文献计量分析
J Multidiscip Healthc. 2024 Nov 12;17:5117-5137. doi: 10.2147/JMDH.S495330. eCollection 2024.
6
Role of Sphingosine-1-Phosphate Signaling Pathway in Pancreatic Diseases.鞘氨醇-1-磷酸信号通路在胰腺疾病中的作用。
Int J Mol Sci. 2024 Oct 25;25(21):11474. doi: 10.3390/ijms252111474.
7
Emerging Roles for Sphingolipids in Cardiometabolic Disease: A Rational Therapeutic Target?鞘脂类在心脏代谢疾病中的新兴作用：合理的治疗靶点？
Nutrients. 2024 Sep 28;16(19):3296. doi: 10.3390/nu16193296.
8
Tissue Engineered 3D Constructs for Volumetric Muscle Loss.用于容积性肌肉丧失的组织工程化 3D 构建体
Ann Biomed Eng. 2024 Sep;52(9):2325-2347. doi: 10.1007/s10439-024-03541-w. Epub 2024 Jul 31.
9
Cancer immunometabolism: advent, challenges, and perspective.癌症免疫代谢：起源、挑战与展望。
Mol Cancer. 2024 Apr 5;23(1):72. doi: 10.1186/s12943-024-01981-5.
10
Abnormal Lymphatic Sphingosine-1-Phosphate Signaling Aggravates Lymphatic Dysfunction and Tissue Inflammation.异常的淋巴鞘氨醇-1-磷酸信号转导加重淋巴管功能障碍和组织炎症。
Circulation. 2023 Oct 17;148(16):1231-1249. doi: 10.1161/CIRCULATIONAHA.123.064181. Epub 2023 Aug 23.
本文引用的文献
1
Dynamic molecular processes mediate cellular mechanotransduction.动态分子过程介导细胞力学转导。
Nature. 2011 Jul 20;475(7356):316-23. doi: 10.1038/nature10316.
2
Many ceramides.许多神经酰胺。
J Biol Chem. 2011 Aug 12;286(32):27855-62. doi: 10.1074/jbc.R111.254359. Epub 2011 Jun 21.
3
Selectivity and specificity of sphingosine 1-phosphate receptor ligands: "off-targets" or complex pharmacology?1-磷酸鞘氨醇受体配体的选择性和特异性：“脱靶效应”还是复杂药理学？
Front Pharmacol. 2011 May 31;2:26. doi: 10.3389/fphar.2011.00026. eCollection 2011.
4
Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects.鞘氨醇-1-磷酸受体配体的选择性和特异性：表征受体介导效应时的注意事项与批判性思考
Front Pharmacol. 2011 Feb 22;2:9. doi: 10.3389/fphar.2011.00009. eCollection 2011.
5
The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement.鞘氨醇 1-磷酸受体 S1P₂ 维持生发中心 B 细胞的内稳态，并促进龛位限制。
Nat Immunol. 2011 Jun 5;12(7):672-80. doi: 10.1038/ni.2047.
6
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M.高密度脂蛋白相关载脂蛋白 M 提供的内皮保护型神经鞘氨醇-1-磷酸。
Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9613-8. doi: 10.1073/pnas.1103187108. Epub 2011 May 23.
7
Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass.缺乏溶血磷脂酸受体 LPA1 会导致骨骼发育异常和骨量减少。
Bone. 2011 Sep;49(3):395-403. doi: 10.1016/j.bone.2011.04.018. Epub 2011 May 1.
8
Engagement of S1P₁-degradative mechanisms leads to vascular leak in mice.S1P₁ 降解机制的参与导致小鼠血管渗漏。
J Clin Invest. 2011 Jun;121(6):2290-300. doi: 10.1172/JCI45403. Epub 2011 May 9.
9
Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1.溶血磷脂酸激活过氧化物酶体增殖物激活受体-γ在过表达甘油-3-磷酸酰基转移酶-1 的 CHO 细胞中。
PLoS One. 2011 Apr 20;6(4):e18932. doi: 10.1371/journal.pone.0018932.
10
Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium.脂蛋白衍生的溶血磷脂酸通过从内皮细胞释放 CXCL1 促进动脉粥样硬化。
Cell Metab. 2011 May 4;13(5):592-600. doi: 10.1016/j.cmet.2011.02.016.
Zotero 插件