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Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.

作者信息

Blaho Victoria A, Hla Timothy

机构信息

Center for Vascular Biology, Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York 10065, USA.

出版信息

Chem Rev. 2011 Oct 12;111(10):6299-320. doi: 10.1021/cr200273u. Epub 2011 Sep 22.

DOI:10.1021/cr200273u
PMID:21939239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3216694/
Abstract
摘要

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本文引用的文献

1
Dynamic molecular processes mediate cellular mechanotransduction.动态分子过程介导细胞力学转导。
Nature. 2011 Jul 20;475(7356):316-23. doi: 10.1038/nature10316.
2
Many ceramides.许多神经酰胺。
J Biol Chem. 2011 Aug 12;286(32):27855-62. doi: 10.1074/jbc.R111.254359. Epub 2011 Jun 21.
3
Selectivity and specificity of sphingosine 1-phosphate receptor ligands: "off-targets" or complex pharmacology?1-磷酸鞘氨醇受体配体的选择性和特异性：“脱靶效应”还是复杂药理学？
Front Pharmacol. 2011 May 31;2:26. doi: 10.3389/fphar.2011.00026. eCollection 2011.
4
Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects.鞘氨醇-1-磷酸受体配体的选择性和特异性：表征受体介导效应时的注意事项与批判性思考
Front Pharmacol. 2011 Feb 22;2:9. doi: 10.3389/fphar.2011.00009. eCollection 2011.
5
The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement.鞘氨醇 1-磷酸受体 S1P₂ 维持生发中心 B 细胞的内稳态，并促进龛位限制。
Nat Immunol. 2011 Jun 5;12(7):672-80. doi: 10.1038/ni.2047.
6
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M.高密度脂蛋白相关载脂蛋白 M 提供的内皮保护型神经鞘氨醇-1-磷酸。
Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9613-8. doi: 10.1073/pnas.1103187108. Epub 2011 May 23.
7
Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass.缺乏溶血磷脂酸受体 LPA1 会导致骨骼发育异常和骨量减少。
Bone. 2011 Sep;49(3):395-403. doi: 10.1016/j.bone.2011.04.018. Epub 2011 May 1.
8
Engagement of S1P₁-degradative mechanisms leads to vascular leak in mice.S1P₁ 降解机制的参与导致小鼠血管渗漏。
J Clin Invest. 2011 Jun;121(6):2290-300. doi: 10.1172/JCI45403. Epub 2011 May 9.
9
Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1.溶血磷脂酸激活过氧化物酶体增殖物激活受体-γ在过表达甘油-3-磷酸酰基转移酶-1 的 CHO 细胞中。
PLoS One. 2011 Apr 20;6(4):e18932. doi: 10.1371/journal.pone.0018932.
10
Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium.脂蛋白衍生的溶血磷脂酸通过从内皮细胞释放 CXCL1 促进动脉粥样硬化。
Cell Metab. 2011 May 4;13(5):592-600. doi: 10.1016/j.cmet.2011.02.016.