Radiology Department, Robert Jones and Agnes Hunt Orthopaedic and District Hospitals NHS Trust, Gobowen, Oswestry, Shropshire, UK.
Clin Radiol. 2012 Mar;67(3):195-206. doi: 10.1016/j.crad.2011.08.014. Epub 2011 Sep 21.
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) is an umbrella acronym for inflammatory clinical conditions whose common denominator is aseptic osteoarticular involvement with characteristic skin lesions. It involves all ages, can involve any skeletal site, and has variable imaging appearances depending on the stage/age of the lesion and imaging method. It mimics important differentials including infection and neoplasia. Awareness of the imaging features, especially in the spine, facilitates early diagnosis, prevents repeated biopsies, and avoids unnecessary surgery, while initiating appropriate treatment.
SAPHO（滑膜炎、痤疮、脓疱病、骨肥厚和骨炎）是一种炎症性临床疾病的总称，其共同特征是无菌性骨关节炎累及特征性皮肤病变。它可发生于所有年龄段，可累及任何骨骼部位，且其影像学表现具有多变性，取决于病变的阶段/年龄和影像学方法。它类似于包括感染和肿瘤在内的重要鉴别诊断。了解影像学特征，特别是在脊柱方面，有助于早期诊断，防止反复活检和避免不必要的手术，同时启动适当的治疗。
