Chen Li-ping, Li Chuan, Wang Chuan, Wen Tian-fu, Yan Lu-nan, Li Bo
Sichuan University, Chengdu, China.
Hepatogastroenterology. 2012 Jan-Feb;59(113):292-5. doi: 10.5754/hge11399.
BACKGROUND/AIMS: To identify risk factors of postoperative ascites after hepatectomy for patients with hepatocellular carcinoma (HCC) and hepatitis B virus associated-cirrhosis.
The data of 73 patients were reviewed in current study. Pre- and intra-operative variables were retrospectively analyzed using uni- and multi-variate analyses. The diagnostic accuracy of the predictors was evaluated by the receiver operating characteristics (ROC) analysis.
Indocyanine green retention rate at 15 minutes (ICGR15) >10%, tumor size >10cm, splenectomy, middle hepatic vein (MHV) resection, red blood cell (RBC) transfusion were risk factors in univariate analysis. However, only ICGR15 >10%, tumor size >10cm and RBC transfusion showed prognostic power in multivariate analysis. ROC analysis suggested the best cut-off value of risk factors was 2.
Our study indicated the postoperative ascites could be predicted by pre- and intra-operative variables. ICGR15 >10%, tumor size >10cm and RBC transfusion were independent risk factors for ascites after hepatectomy. Patients with two or more of the above-mentioned risk factors may suffer postoperative ascites after hepatectomy.
背景/目的：确定肝细胞癌（HCC）合并乙型肝炎病毒相关性肝硬化患者肝切除术后腹水的危险因素。
本研究回顾了73例患者的数据。采用单因素和多因素分析对术前和术中变量进行回顾性分析。通过受试者工作特征（ROC）分析评估预测指标的诊断准确性。
单因素分析显示，15分钟吲哚菁绿滞留率（ICGR15）>10%、肿瘤大小>10cm、脾切除术、肝中静脉（MHV）切除、红细胞（RBC）输血是危险因素。然而，多因素分析中只有ICGR15>10%、肿瘤大小>10cm和RBC输血显示出预后价值。ROC分析表明危险因素的最佳截断值为2。
我们的研究表明，术后腹水可通过术前和术中变量进行预测。ICGR15>10%、肿瘤大小>10cm和RBC输血是肝切除术后腹水的独立危险因素。具有上述两种或更多危险因素的患者肝切除术后可能发生腹水。
