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选择性入肝血流阻断对腹腔镜左半肝切除术血流动力学状况的影响 选择性入肝血流阻断对腹腔镜左半肝切除术血流动力学状况的影响。

Effect of selective inflow occlusion on hemodynamic conditions during laparoscopic left hemihepatectomy effect of selective inflow occlusion on hemodynamic conditions during laparoscopic left hemihepatectomy.

作者信息

Yan Chun-Yan, Cai Xiu-Jun, Wang Yi-Fan

机构信息

Department of Anesthesiology, Zhejiang University, Hangzhou, China.

出版信息

Hepatogastroenterology. 2012 Mar-Apr;59(114):501-4. doi: 10.5754/hge11462.

DOI:10.5754/hge11462
PMID:21940378
Abstract

BACKGROUND/AIMS: Selective inflow occlusion instead of portal triad clamping was used during laparoscopic left hemihepatectomy in our institution. This study observed its hemodynamic effects during operation.

METHODOLOGY

Hemodynamic parameters including heart rate (HR), mean arterial pressure (MAP), central venous pressure (CVP), mean pulmonary artery pressure (PAP), pulmonary capillary wedge pressure (PCWP), cardiac index (CI), systemic vascular resistance (SVR) and pulmonary vascular resistance (PVR) were collected at 6 time points: after induction, after insufflation with CO2, after patient in reverse Trendelenburg position, after left branch of hepatic artery was occluded, after left branch of portal vein was occluded and after desufflation with patient supine.

RESULTS

No severe perioperative cardiopulmonary complications were observed. Occlusion of left branch of hepatic artery brought no significant hemodynamic change. Occlusion of left branch of portal vein increased CVP and CI and decreased SVR. CO2 inflation caused HR, MAP and SVR to increase. The change to reverse Trendelenburg position caused CVP and PAP to decrease. When placed in the supine position with deflation, MAP, CVP, PAP, PCWP and CI went to a higher than base level. HR and SVR returned to base level.

CONCLUSIONS

Using selective inflow occlusion in laparoscopic left hemihepatectomy caused few hemodynamic changes before and after occlusion in patients without cardiopulmonary diseases. However, the change of position and inflation or deflation caused significant changes.

摘要

背景/目的:在我院进行腹腔镜左半肝切除术时采用选择性入肝血流阻断而非肝门三联阻断。本研究观察了其术中的血流动力学效应。

方法

在6个时间点收集血流动力学参数,包括心率(HR)、平均动脉压(MAP)、中心静脉压(CVP)、平均肺动脉压(PAP)、肺毛细血管楔压(PCWP)、心脏指数(CI)、全身血管阻力(SVR)和肺血管阻力(PVR):诱导后、二氧化碳气腹后、患者处于头低脚高位后、肝动脉左支阻断后、门静脉左支阻断后以及患者仰卧位放气后。

结果

未观察到严重的围手术期心肺并发症。肝动脉左支阻断未引起明显的血流动力学变化。门静脉左支阻断使CVP和CI升高,SVR降低。二氧化碳气腹使HR、MAP和SVR升高。改为头低脚高位使CVP和PAP降低。放气仰卧位时,MAP、CVP、PAP、PCWP和CI高于基础水平。HR和SVR恢复至基础水平。

结论

在无心肺疾病的患者中,腹腔镜左半肝切除术中采用选择性入肝血流阻断在阻断前后引起的血流动力学变化较少。然而,体位改变和气腹或放气会引起显著变化。

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