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从肾患者血流感染的耐甲氧西林金黄色葡萄球菌分离株中进行 DNA 微阵列基因分型和毒力以及抗菌药物耐药基因分析。

DNA microarray genotyping and virulence and antimicrobial resistance gene profiling of methicillin-resistant Staphylococcus aureus bloodstream isolates from renal patients.

机构信息

Department of Clinical Microbiology, RCSI Education and Research Centre, Smurfit Building, Beaumont Hospital, Dublin 9, Ireland.

出版信息

J Clin Microbiol. 2011 Dec;49(12):4349-51. doi: 10.1128/JCM.05017-11. Epub 2011 Sep 21.

DOI:10.1128/JCM.05017-11
PMID:21940465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3232979/
Abstract

Thirty-six methicillin-resistant Staphylococcus aureus (MRSA) bloodstream isolates from renal patients were genetically characterized by DNA microarray analysis and spa typing. The isolates were highly clonal, belonging mainly to ST22-MRSA-IV. The immune evasion and enterotoxin gene clusters were found in 29/36 (80%) and 33/36 (92%) isolates, respectively.

摘要

36 株耐甲氧西林金黄色葡萄球菌（MRSA）血流感染分离株通过 DNA 微阵列分析和 spa 分型进行了遗传特征分析。这些分离株具有高度的克隆性，主要属于 ST22-MRSA-IV 型。29/36（80%）和 33/36（92%）分离株分别携带免疫逃逸和肠毒素基因簇。

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