维生素D作为一种药物。

Vitamin D as a drug.

作者信息

Bagnoli Franco, Casucci Martina, Rossetti Annalisa, Nappini Sara, Cecchi Sara, Toti Stefania, Franci Maria Beatrice

机构信息

Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Italy.

出版信息

J Matern Fetal Neonatal Med. 2011 Oct;24 Suppl 1:7-11. doi: 10.3109/14767058.2011.607559.

DOI:10.3109/14767058.2011.607559

PMID:21942582

Abstract

Vitamin D has an important role in bone-metabolism (and its deficiency can cause preterm osteopenia, craniotabe and rickets), but it has also non-calcitropic functions. In fact, vitamin D deficiency is correlated to chronic kidney disease, respiratory infections, type 1 diabetes, psoriasis, Crohn disease and neonatal hypocalcemia. Because of the vitamin D deficiency is a global problem, its role as a drug is fundamental for the human health in all ages.

摘要

维生素D在骨代谢中起重要作用（其缺乏可导致早产性骨质减少、颅骨软化和佝偻病），但它也具有非钙调节功能。事实上，维生素D缺乏与慢性肾病、呼吸道感染、1型糖尿病、银屑病、克罗恩病和新生儿低钙血症相关。由于维生素D缺乏是一个全球性问题，其作为一种药物的作用对所有年龄段的人类健康都至关重要。