Schüller J
I. Medizinischen Abteilung des Krankenhauses Rudolfstiftung, Wien.
Wien Med Wochenschr. 1990 Apr 30;140(8):190-4.
The idea to increase the cytostatic concentration by direct perfusion of the target organ and to simultaneously reduce the systemic side effect is almost 40 years old. New techniques brought new impulses to this old method, namely regional chemotherapy, by the discovery of a fully implantable catheter system as a byproduct of space research. This system can be used intravenously, intraarterially and intraperitoneally. In addition to avoid some types of complications caused by externally placed catheters this system serves another important goal in palliative cancer treatment: an improved quality of life, as a good ambulatory implementation is secured.
通过直接灌注靶器官来提高细胞抑制剂浓度并同时减少全身副作用的想法已有近40年历史。新技术为这种古老的方法——区域化疗带来了新的推动，即作为太空研究副产品发现的完全可植入导管系统。该系统可用于静脉内、动脉内和腹腔内。除了避免一些由外置导管引起的并发症外，该系统在姑息性癌症治疗中还服务于另一个重要目标：改善生活质量，因为确保了良好的门诊实施。
