Department of Obstetrics and Gynecology, Aga Khan University Hospital, Nairobi, Kenya.
Int J Gynaecol Obstet. 2011 Dec;115(3):273-6. doi: 10.1016/j.ijgo.2011.07.022. Epub 2011 Sep 23.
To review the histopathologic diagnosis of biopsies taken following visualization of endometriosis at laparoscopy and to correlate visual with microscopic diagnoses.
A retrospective review was undertaken of medical charts with a diagnosis of endometriosis at Aga Khan University Hospital, Nairobi, Kenya, between January 2001 and October 2010. Eligibility included visual diagnosis of endometriosis at laparoscopy, with a clear record of site, size, morphology, and number of lesions. The histopathologic diagnosis of the biopsies sampled was sought. Correlation was undertaken using κ statistics for diagnostic variability.
Of the 204 relevant records, 152 (74.5%) met the eligibility criteria; from these cases, 239 specimens were submitted for histology. The most common symptom was chronic pelvic pain (108 [71.1%]). Most biopsies were obtained from the ovary and posterior cul-de-sac. Histopathologic diagnosis was confirmed in (152 [63.8%]) specimens and correlated with Asian race, multiparity, and chronic pelvic pain. Neither the site of the lesion nor the stage of disease influenced the histopathologic diagnosis.
Laparoscopic visualization of endometriosis does not always correlate with histopathologic diagnosis; several other lesions may mimic endometriosis on histopathologic examination.
回顾腹腔镜下观察到子宫内膜异位症后活检的组织病理学诊断，并将肉眼与显微镜下的诊断进行相关性分析。
对肯尼亚内罗毕 Aga Khan 大学医院 2001 年 1 月至 2010 年 10 月期间的病历进行了回顾性分析，这些病历均有子宫内膜异位症的肉眼诊断，并明确记录了病变的部位、大小、形态和数量。寻找活检样本的组织病理学诊断。采用 κ 统计量进行诊断变异性的相关性分析。
在 204 份相关记录中，有 152 份（74.5%）符合入选标准；从这些病例中，有 239 份标本被送检进行组织学检查。最常见的症状是慢性盆腔痛（108 例[71.1%]）。大多数活检来自卵巢和后穹窿。在 152 份（63.8%）标本中证实了组织病理学诊断，并与亚洲种族、多产和慢性盆腔痛相关。病变部位和疾病分期均未影响组织病理学诊断。
腹腔镜下观察到的子宫内膜异位症并不总是与组织病理学诊断相符；在组织病理学检查中，还有其他几种病变可能模拟子宫内膜异位症。
