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腕管综合征和腕部尺神经病变:共病还是不共病?

Carpal tunnel syndrome and ulnar neuropathy at the wrist: comorbid disease or not?

机构信息

Medical Faculty, Department of Neurology, Adnan Menderes University, Aydin, Türkiye.

出版信息

J Clin Neurophysiol. 2011 Oct;28(5):520-3. doi: 10.1097/WNP.0b013e318231c2cc.

DOI:10.1097/WNP.0b013e318231c2cc
PMID:21946366
Abstract

The aim of this study was to elucidate the possible association between carpal tunnel syndrome (CTS) and ulnar neuropathy at the wrist because of the contradictory results of previous studies. Thus, a retrospective case-control study was arranged with an electromyographic database including patients between 2003 and 2009. Patients were selected according to initial diagnosis and the examiner's criteria, and data were plotted by computer. One thousand nine hundred twenty-four patients were evaluated for CTS and 1,024 patients for diabetic CTS or diabetic polyneuropathy. CTS and ulnar neuropathy co-occurrence and CTS alone at the wrist was found in 54/404, 19/50, 20/27 patients, respectively. Logistic regression analysis revealed that having CTS was associated with a doubled risk of ulnar neuropathy at the wrist in both idiopathic CTS and diabetic CTS groups but not in diabetic polyneuropathy. Being male and of advanced age were other risk factors for ulnar neuropathy at the wrist. Correlation analysis (age and sex were controlled) revealed decreased but significant correlations between median and ulnar sensory amplitudes in CTS cases in all groups.

摘要

本研究旨在阐明腕管综合征 (CTS) 和腕部尺神经病变之间可能存在的关联,因为之前的研究结果存在矛盾。因此,我们进行了一项回顾性病例对照研究,该研究的电生理数据库纳入了 2003 年至 2009 年间的患者。根据最初的诊断和检查者的标准选择患者,并通过计算机绘制数据。共评估了 1924 例 CTS 患者和 1024 例糖尿病性 CTS 或糖尿病多发性神经病患者。结果发现,54/404、19/50 和 20/27 例患者分别存在 CTS 和尺神经病变共存、单纯 CTS 和单纯尺神经病变。Logistic 回归分析显示,在特发性 CTS 和糖尿病性 CTS 组中,患有 CTS 会使患腕部尺神经病变的风险增加一倍,但在糖尿病多发性神经病组中则不然。男性和年龄较大也是腕部尺神经病变的其他危险因素。相关性分析(控制年龄和性别)显示,在所有组中,CTS 患者的正中神经和尺神经感觉波幅均存在显著但降低的相关性。

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