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经验性抗真菌治疗:侵袭性真菌感染的有效替代方案

Empirical antifungal treatment: a valid alternative for invasive fungal infection.

作者信息

Vallejo C, Barberán J

机构信息

Servicio de Hematología, Hospital Central de Asturias, Oviedo, Spain.

出版信息

Rev Esp Quimioter. 2011 Sep;24(3):117-22.

PMID:21947092
Abstract

Empirical antifungal therapy refers to initiation of an antifungal agent at the first possible clinical evidence of fungal infection. It is frequently recommended in neutropenic high-risk hematological patients of invasive fungal infection in order to guarantee an early approach. An extensive review is made of therapeutic advances and scientific evidence in this setting. Specific recommendations for use and criteria for selection of antifungal agents are discussed.

摘要

经验性抗真菌治疗是指在出现真菌感染的首个可能临床证据时开始使用抗真菌药物。对于有侵袭性真菌感染风险的中性粒细胞减少的血液系统高危患者,经常建议采用这种治疗方法,以确保早期治疗。本文对这方面的治疗进展和科学证据进行了广泛综述。文中还讨论了抗真菌药物的具体使用建议和选择标准。

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Clin Exp Otorhinolaryngol. 2014 Sep;7(3):181-7. doi: 10.3342/ceo.2014.7.3.181. Epub 2014 Aug 1.