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[脊柱神经根鞘肿瘤]

[Tumours of the nerve root sheath in the spine].

作者信息

Gelabert-González Miguel, Castro-Bouzas Daniel, Serramito-García Ramón, Santín-Amo José M, Arán-Echabe Eduardo, Prieto-González Ángel, Allut Alfredo G

机构信息

Departamento de Cirugía, Universidad de Santiago de Compostela, Servicio de Neurocirugía, Hospital Clínico Universitario, Santiago de Compostela, A Coruña, España.

出版信息

Rev Neurol. 2011 Oct 1;53(7):390-6.

PMID:21948009
Abstract

INTRODUCTION

Spinal schwannomas account for about 30% of intradural spinal cord tumors in adults. More are solitary tumors, which can occur throughout the spinal canal. The multiple form of neurofibromas is known as von Recklinghausen disease. AIM. To analyze clinical and radiologic characteristics, treatment and evolution of patients with spinal nerve sheath tumor.

PATIENTS AND METHODS

This was a retrospective study in a series of patients treated surgically of spinal schwannomas during 25 years. The following variables were evaluated: gender, age, symptomatology, radiological findings, localization, surgical findings and results.

RESULTS

We treated 35 male and 33 female with a mean age of 55 years (range: 12-76 years).The most common pre-surgical symptom was local or radicular pain in 55 patients (80.8%). In 49 cases (66.2%), the tumor was sited in the lumbosacral, in 15 cases (20.2%) in the dorsal tract, and in 10 cases (13.6%) in the cervical tract. Total removal was achieved in 70 cases (94.5%) and subtotal resection in 4 (5.5%). 66 tumors (89.1%) were schwannomas and the other 8 cases (10.9%) neurofibromas.

CONCLUSIONS

Tumors of the spinal root sheaths can occur at any level of the spinal canal. Most patients present with local and/or radicular pain and in most cases total resection its possible with good functional recovery.

摘要

引言

脊髓神经鞘瘤约占成人硬脊膜内脊髓肿瘤的30%。更多的是孤立性肿瘤,可发生于整个椎管。神经纤维瘤的多发形式被称为冯雷克林霍增氏病。目的:分析脊神经鞘瘤患者的临床和放射学特征、治疗及病情演变。

患者与方法

这是一项对25年间接受脊髓神经鞘瘤手术治疗的一系列患者的回顾性研究。评估了以下变量:性别、年龄、症状、放射学检查结果、肿瘤位置、手术所见及结果。

结果

我们治疗了35名男性和33名女性患者,平均年龄55岁(范围:12 - 76岁)。最常见的术前症状是局部或神经根性疼痛,共55例(80.8%)。49例(66.2%)肿瘤位于腰骶部,15例(20.2%)位于背侧束,10例(13.6%)位于颈部束。70例(94.5%)实现了全切,4例(5.5%)为次全切除。66例肿瘤(89.1%)为神经鞘瘤,另外8例(10.9%)为神经纤维瘤。

结论

脊神经根鞘肿瘤可发生于椎管的任何节段。大多数患者表现为局部和/或神经根性疼痛,大多数情况下可实现全切并伴有良好的功能恢复。

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