Cope Austin, Eggert Joan V, O'Brien Erin
Texas Tech University, Lubbock, USA.
Diving Hyperb Med. 2011 Sep;41(3):135-8.
We describe a case series of 11 patients with retinal artery occlusion treated with hyperbaric oxygen therapy (HBOT) at Intermountain Dixie Regional Medical Center between 2005 and 2009. We then combined data from our case series with data from two other case series to report on a combined total of 51 patients.
Eight of our 11 patients achieved improved visual acuity. Analysis of the combined case series showed that 74 % of patients treated with HBOT had improvement in visual acuity (P < 0.0001) with 53 % improving two lines or more on a modified Snellen value. The combined case series also showed that visual acuity improved in all time-from-occlusion to treatment categories, ranging from less than 8 hours to six days.
We recommend consideration of HBOT for patients who present with recent retinal artery occlusion. Hyperbaric centres treating these patients should consider forming a central registry of standardised data to prospectively study the results of therapy.
我们描述了2005年至2009年间在山间迪克西地区医疗中心接受高压氧治疗（HBOT）的11例视网膜动脉阻塞患者的病例系列。然后，我们将我们病例系列的数据与另外两个病例系列的数据相结合，报告了总共51例患者的情况。
我们的11例患者中有8例视力得到改善。对合并病例系列的分析表明，接受HBOT治疗的患者中有74%视力得到改善（P<0.0001），其中53%在改良斯内伦视力表上提高了两行或更多。合并病例系列还表明，从阻塞到治疗的所有时间段内视力均有改善，时间范围从少于8小时到6天。
我们建议对近期出现视网膜动脉阻塞的患者考虑采用HBOT治疗。治疗这些患者的高压氧中心应考虑建立标准化数据的中央登记处，以便前瞻性地研究治疗结果。
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