Khiari Ramzi, Ghorbel Jilani, Dridi Mohamed, Maarouf Jamel, Ben Rais Nawfel, Ghozzi Samir
Service d'urologie, Hopital Militaire, Tunis, Tunisie.
Tunis Med. 2011 Aug-Sep;89(8-9):703-8.
To evaluate the Oncological and functional results and to clear risk factors of biochemical recurrence in patients with prostate cancer treated by retropubic prostatectomy.
Retrospective analysis of 50 consecutive retropubic radical prostatectomies performed between January 1999 and january 2008. Biochemical recurrence was defined by PSA > 0.2 ng/ml. Univariate analysis of prognostic factors of biochemical recurrence was performed. The study of the urinary continence and the sexuality is essentially based on a meticulous interrogatory.
The biochemical recurrence-free survival was 68%. Significant risk factors on univariate analysis were: number of positive biopsy, the percentage of positive biopsy, perineural invasion, Gleason score, clinical stage, pathological stage, and tumour volume. On the functional plan, only one patient is totally incontinent. The return to a normal sexuality appears uncertain, the sexual potency was satisfactory among 5 patients (10% of the patients operated and 55,5% of the patients having had a nervesparing techniques)
Our oncological results is acceptable and are quite comparable to literature. This while guaranteeing the satisfactory functional results essentially basing on an acquirement of a continence quasi-perfect.
评估耻骨后前列腺切除术治疗前列腺癌患者的肿瘤学及功能结果,并明确生化复发的危险因素。
回顾性分析1999年1月至2008年1月间连续进行的50例耻骨后根治性前列腺切除术。生化复发定义为前列腺特异抗原(PSA)>0.2 ng/ml。对生化复发的预后因素进行单因素分析。尿失禁和性功能的研究主要基于细致的问诊。
无生化复发生存率为68%。单因素分析的显著危险因素为:阳性活检数量、阳性活检百分比、神经周围侵犯、 Gleason评分、临床分期、病理分期及肿瘤体积。在功能方面,仅1例患者完全尿失禁。恢复正常性功能情况尚不确定,5例患者性功能满意(占手术患者的10%,接受神经保留技术患者的55.5%)。
我们的肿瘤学结果是可接受的,与文献报道相当。同时,在基本保证获得近乎完美的尿失禁控制的基础上,功能结果令人满意。