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[37例血吸虫病患者的系统心脏学研究]

[Systematic cardiologic study in 37 schistosomiasis patients].

作者信息

Bertrand E, Renambot J, Dalger J, Attia Y

出版信息

Sem Hop. 1978;54(43-44):1351-6.

PMID:219489
Abstract
  1. A systematic search was made for cardiac abnormalities (clinical, radiological and EKG) and for haemodynamic disorders (catheterisation of the right side of the heart and pulmonary artery). It was generally found that: -- 14 patients (37.8%) had no symptoms; -- 8 patients (21.6%) had pulmonary arterial hypertension (PAHT) with the corresponding cardiac signs; -- 15 patients (40.5%) had cardiac signs with no evidence of PAHT. 2) The 8 patients with PAHT (21.6%) had precapillary type of PAHT with an arteriocapillary gradient. The symptoms were those of PAHT and of the right ventricular failure; but this desorder could be latent. PAHT can be in relation with inflammatory lesions. In these 8 patients, S. Mansoni was to blame in 6 cases and 5 S. Hematobium in 2. 3) In 9 patients (24.3%), cardiac signs were connected indirectly with bilharziasis by anemia, iatrogenic injury or hypertensive myocardial disease of renal origin. 4) In 3 patients (8.1%), cardiac signs were found because of coexistant disease. 5) In 3 patients (8.1%), cardiac signs could have been due to bilharzia myocarditis. The authors reviewed the experimental and clinical discussions for such a possibility.
摘要
  1. 对心脏异常(临床、放射学和心电图方面)以及血流动力学紊乱(右心和肺动脉导管检查)进行了系统的检查。总体发现如下:——14例患者(37.8%)无症状;——8例患者(21.6%)有肺动脉高压(PAHT)及相应的心脏体征;——15例患者(40.5%)有心脏体征,但无PAHT证据。2) 8例PAHT患者(21.6%)为毛细血管前型PAHT,存在动-毛细血管梯度。症状为PAHT和右心室衰竭的症状;但这种紊乱可能是潜在的。PAHT可能与炎症性病变有关。在这8例患者中,6例归咎于曼氏血吸虫,2例归咎于埃及血吸虫。3) 9例患者(24.3%)的心脏体征通过贫血、医源性损伤或肾源性高血压性心肌病与血吸虫病间接相关。4) 3例患者(8.1%)因合并疾病发现心脏体征。5) 3例患者(8.1%)的心脏体征可能归因于血吸虫性心肌炎。作者回顾了关于这种可能性的实验和临床讨论。

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