Dere W H, Groggel G C
Department of Internal Medicine, Indiana University School of Medicine.
Geriatrics. 1990 Jul;45(7):48-52, 55-6.
Diabetic nephropathy is an important clinical entity in the geriatric population. One half of newly enrolled patients in dialysis programs have non-insulin-dependent diabetes mellitus (NIDDM), and the number of NIDDM patients with chronic renal insufficiency is estimated to be eight times greater than those with insulin-dependent diabetes mellitus. In view of this growth potential, this paper is intended to briefly review the epidemiology and pathogenesis of diabetic nephropathy, and to highlight some important considerations in the clinical evaluation and treatment of patients with NIDDM.
糖尿病肾病是老年人群中的一个重要临床实体。透析项目中新纳入的患者中有一半患有非胰岛素依赖型糖尿病（NIDDM），据估计，患有慢性肾功能不全的NIDDM患者数量是胰岛素依赖型糖尿病患者的八倍。鉴于这种增长潜力，本文旨在简要回顾糖尿病肾病的流行病学和发病机制，并强调在NIDDM患者临床评估和治疗中的一些重要注意事项。
