Suhara T, Azuma S, Hayakawa M, Futamura M, Yoshida A, Kaneda N, Kageyama T, Tanemura H, Furuta T, Saji S
2nd Dept. of Surgery, Gifu Univ. School of Med.
Gan No Rinsho. 1990 Jul;36(8):934-8.
A metastatic malignant melanoma of the stomach is not a disease of rate occurrence, but reports of melanomas that were clinically diagnosed and were treated by a surgical operation are rare. The case presented is a 73-year-old woman, who underwent an excision of a malignant melanoma of the left sole in 1981. Subsequently, she had a subcutaneous metastasis of a melanoma three times and was treated by a resection and immunochemotherapy. In January, 1988, an X-ray examination of stomach revealed a giant elevated lesion, and an endoscopic examination of the stomach revealed a black pigmented tumor with ulceration. A biopsy taken from the tumor confirmed the diagnosis of a malignant melanoma. Thus, she was given a total gastrectomy. Reports in the Japanese literature of metastatic malignant melanomas of the stomach diagnosed while the patient was still living amount to 11 cases. Of this number, 3 patients were given a surgical operation. Further, these 3 patients lived longer than the non-surgically treated cases and had a better quality of remaining life.
胃转移性恶性黑色素瘤并非罕见疾病，但临床诊断并接受手术治疗的黑色素瘤报告却很少。本文报告的病例是一位73岁女性，她于1981年接受了左足底恶性黑色素瘤切除术。随后，她三次出现黑色素瘤皮下转移，并接受了切除和免疫化疗。1988年1月，胃部X线检查发现一个巨大的隆起病变，胃镜检查发现一个有溃疡的黑色色素沉着肿瘤。肿瘤活检确诊为恶性黑色素瘤。因此，她接受了全胃切除术。日本文献中关于患者仍存活时诊断出的胃转移性恶性黑色素瘤的报告共计11例。其中，3例患者接受了手术治疗。此外，这3例患者的存活时间比未接受手术治疗的病例更长，剩余生活质量也更好。
