Departamento de Microbiología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, Colombia.
J Bacteriol. 2011 Oct;193(20):5866-7. doi: 10.1128/JB.05928-11.
We report the first whole-genome sequence of the Mycobacterium colombiense type strain, CECT 3035, which was initially isolated from Colombian HIV-positive patients and causes respiratory and disseminated infections. Preliminary comparative analyses indicate that the M. colombiense lineage has experienced a substantial genome expansion, possibly contributing to its distinct pathogenic capacity.
我们报告了首株哥伦比亚分枝杆菌模式株 CECT 3035 的全基因组序列，该菌最初从哥伦比亚 HIV 阳性患者中分离得到，可引起呼吸道和播散性感染。初步比较分析表明，哥伦比亚分枝杆菌谱系经历了大规模的基因组扩张，这可能有助于其独特的致病性。
