Yankowitz J, Leake J, Huggins G, Gazaway P, Gates E
Department of Gynecology and Obstetrics, Johns Hopkins University, Francis Scott Key Medical Center, Baltimore, Maryland 21224.
Obstet Gynecol Surv. 1990 Jul;45(7):405-14.
Methotrexate with folinic acid rescue was used to terminate a clinically diagnosed cervical pregnancy while preserving reproductive capability in a young female patient. The chemotherapy was well tolerated except for transient elevation of liver enzymes. Beta HCG titers fell rapidly and became negative by 13 days. This is the first report showing successful treatment of a cervical pregnancy with single-dose chemotherapy. The literature is reviewed and discussed.
采用甲氨蝶呤联合亚叶酸钙解救治疗一名临床诊断为宫颈妊娠的年轻女性患者，以终止妊娠并保留其生殖能力。除肝酶短暂升高外，化疗耐受性良好。β-HCG水平迅速下降，至13天时转为阴性。这是首例单剂量化疗成功治疗宫颈妊娠的报告。本文对相关文献进行了回顾和讨论。
