Department of Medicine & Therapeutics, Prince of Wales Hospital, the Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Disabil Rehabil. 2011;33(21-22):1990-6. doi: 10.3109/09638288.2011.553709.
Limitations in participation may have independent influences on health-related quality of life (HRQOL) at early and late phases of stroke recovery.
Consecutive stroke patients were interviewed at months 3 and 12 after stroke for modified Barthel Index (MBI), geriatric depression scale (GDS) and WHO QOL questionnaire (abbreviated Hong Kong version). London handicap scale (LHS) was used to measure limitations in participation. The influence of the six LHS domains on the four HRQOL domains, adjusted for MBI and GDS was analysed by structural equation modelling with a two-component analysis.
Complete data were collected in 500 and 433 subjects at months 3 and 12, respectively. On multivariate analysis, after adjustment for MBI and GDS, the independence and social integration domains of LHS had significant influence on physical and social HRQOL, respectively, at both 3 and 12 months post-stroke. The occupation domain was a significant factor of physical and environmental HRQOL at month 12, but not at month 3. Economic sufficiency had more influence on HRQOL at month 3 than at month 12. The mobility and orientation domains had no significant negative influence on HRQOL.
In stroke patients, participation had significant independent influences on HRQOL.
参与能力的限制可能对中风康复早期和晚期的健康相关生活质量（HRQOL）有独立的影响。
连续的中风患者在中风后 3 个月和 12 个月接受改良巴氏指数（MBI）、老年抑郁量表（GDS）和世界卫生组织生活质量问卷（缩写为香港版）访谈。伦敦残障量表（LHS）用于测量参与能力的限制。使用结构方程模型和双成分分析，对 LHS 的六个领域对四个 HRQOL 领域的影响进行分析，调整了 MBI 和 GDS。
在 3 个月和 12 个月时，分别有 500 名和 433 名患者完成了完整的数据收集。多变量分析显示，在调整 MBI 和 GDS 后，LHS 的独立性和社会融合领域在中风后 3 个月和 12 个月时分别对身体和社会 HRQOL 有显著影响。职业领域是 12 个月时身体和环境 HRQOL 的重要因素，但 3 个月时不是。经济充足度对 3 个月时的 HRQOL 影响大于 12 个月时。移动和定向领域对 HRQOL 没有显著的负面影响。
在中风患者中，参与能力对 HRQOL 有显著的独立影响。
