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Rectal gonorrhea and chlamydia reinfection is associated with increased risk of HIV seroconversion.直肠淋病和衣原体再感染与 HIV 血清转换风险增加相关。

J Acquir Immune Defic Syndr. 2010 Apr 1;53(4):537-43. doi: 10.1097/QAI.0b013e3181c3ef29.

2

Prevalence, incidence and risk factors for pharyngeal gonorrhoea in a community-based HIV-negative cohort of homosexual men in Sydney, Australia.澳大利亚悉尼基于社区的 HIV 阴性同性恋男性队列中咽淋病的流行率、发病率和危险因素。

Sex Transm Infect. 2010 Apr;86(2):90-6. doi: 10.1136/sti.2009.036814. Epub 2009 Oct 19.

3

Anal sexually transmitted infections and risk of HIV infection in homosexual men.分析性传播感染与男同性恋者 HIV 感染的风险。

J Acquir Immune Defic Syndr. 2010 Jan;53(1):144-9. doi: 10.1097/QAI.0b013e3181b48f33.

4

Nucleic acid amplification tests in the diagnosis of chlamydial and gonococcal infections of the oropharynx and rectum in men who have sex with men.核酸扩增检测在诊断男男性行为者口咽部和直肠衣原体及淋病奈瑟菌感染中的应用

Sex Transm Dis. 2008 Jul;35(7):637-42. doi: 10.1097/OLQ.0b013e31817bdd7e.

5

Evaluation of opa-based real-time PCR for detection of Neisseria gonorrhoeae.基于opa的实时聚合酶链反应检测淋病奈瑟菌的评估。

Sex Transm Dis. 2005 Mar;32(3):199-202. doi: 10.1097/01.olq.0000154495.24519.bf.

6

Validation of roche COBAS Amplicor assay for detection of Chlamydia trachomatis in rectal and pharyngeal specimens by an omp1 PCR assay.通过omp1聚合酶链反应检测法验证罗氏COBAS Amplicor检测法对直肠和咽部标本中沙眼衣原体的检测效果。

J Clin Microbiol. 2004 Jan;42(1):239-41. doi: 10.1128/JCM.42.1.239-241.2004.

7

Increased sensitivity of DNA amplification testing for the detection of pharyngeal gonorrhea in men who have sex with men.用于检测男男性行为者咽部淋病的DNA扩增检测的敏感性提高。

Clin Infect Dis. 2002 Jan 15;34(2):173-6. doi: 10.1086/338236. Epub 2001 Dec 7.

8

Rectal gonorrhoea as an independent risk factor for HIV infection in a cohort of homosexual men.在一组男同性恋者中，直肠淋病是艾滋病毒感染的一个独立危险因素。

Genitourin Med. 1995 Jun;71(3):150-4. doi: 10.1136/sti.71.3.150.

男性性工作者咽部分泌物和直肠内淋球菌载量的差异：对淋球菌检测、传播和控制的影响。

Differing Neisseria gonorrhoeae bacterial loads in the pharynx and rectum in men who have sex with men: implications for gonococcal detection, transmission, and control.

机构信息

Melbourne Sexual Health Centre, 580 Swanston Street, Carlton, Victoria, Australia 3053.

出版信息

J Clin Microbiol. 2011 Dec;49(12):4304-6. doi: 10.1128/JCM.05341-11. Epub 2011 Sep 28.

DOI:10.1128/JCM.05341-11

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3232985/

Abstract

The bacterial loads for gonococcal infections of the pharynx and rectum were determined among men with male sexual partners. The median bacterial load for rectal infections (18,960 copies/swab) was significantly higher than the load for pharyngeal infections (2,100 copies/swab; P = 0.001). Bacterial loads among men with symptomatic proctitis were strikingly high (median, 278,000 copies/swab).

摘要

本研究旨在确定男性性伴侣人群中咽和直肠淋球菌感染的细菌载量。直肠感染的中位细菌载量（18960 拷贝/拭子）显著高于咽感染的载量（2100 拷贝/拭子；P=0.001）。有直肠炎症状的男性的细菌载量高得惊人（中位数为 278000 拷贝/拭子）。