Andersen Kjeld, Ravn Pernille, Bangsborg Jette
Neurologisk Afdeling, Rigshospitalet, Denmark.
Ugeskr Laeger. 2011 Sep 26;173(39):2423-4.
A Danish 73 year-old male patient with polymyalgia rheumatica and in prednisone treatment presented with a cutaneous ulcer on the hand caused by a scratch from a pigeon. Initial treatment with antibiotics was unsuccessful. Biopsy revealed Cryptococcus neoformans and the patient recovered on antifungal treatment. Primary cutaneous cryptococcosis is a rare manifestation of a C. neoformans infection. This case exemplifies the importance of differential diagnosis in immunosuppressed patients who do not respond to a given treatment.
一名73岁的丹麦男性患者,患有风湿性多肌痛,正在接受泼尼松治疗,因被鸽子抓伤手部而出现皮肤溃疡。最初使用抗生素治疗未成功。活检显示为新型隐球菌,患者接受抗真菌治疗后康复。原发性皮肤隐球菌病是新型隐球菌感染的一种罕见表现。该病例体现了对特定治疗无反应的免疫抑制患者进行鉴别诊断的重要性。