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[CT评估头颈部肿瘤颈部淋巴结的预测能力]

[Predictive ability of the CT to evaluate cervical lymph nodes in head and neck tumours].

作者信息

Iñarra Unzurrunzaga Esther, Gorriño Angulo Miren, Vidales Arechaga Luisa, Aguirre Larracoechea Urko, Iriondo Bedialauneta Juan Ramón

机构信息

Servicio de Otorrinolaringología, Hospital Galdakao-Usansolo, Galdakao, Vizcaya, España.

出版信息

Acta Otorrinolaringol Esp. 2011 Nov-Dec;62(6):443-7. doi: 10.1016/j.otorri.2011.06.004. Epub 2011 Sep 28.

Abstract

OBJECTIVE

The aim of this study was to determine the predictive value of computed tomography (CT) i.e., its sensitivity and specificity in detecting metastatic lymph nodes of head and neck tumours. We also studied the capacity of CT in correct nodal staging.

PATIENTS AND METHODS

A CT was performed on 95 patients diagnosed with neoplastic disease of the pharynx and/or larynx. All patients subsequently underwent cervical lymph node dissections. In the imaging study, the following parameters were considered for suspected radiological nodal involvement: lymph node diameter greater than 10mm, lesion margins poorly defined, capsule enhancement after contrast administration and lymph nodes that, despite their size, had signs of central necrosis.

RESULTS

In the dissections, 70.53% resulted N+ in the histological study. The sensitivity of CT was 82.09% and the specificity, 85.71%. The CT detected positivity in 55 of the 67 histologically pathological dissections, while the CT detected negativity in 24 of the 28 dissections histologically negative. The weighted kappa index value was 0.6408, indicating limited capacity for appropriate staging of the lymph nodes.

CONCLUSIONS

While the ability of CT to detect metastatic lymph nodes in head and neck tumours is quite acceptable, it is less so for correctly staging them. It is therefore necessary to look for other imaging tests that provide greater accuracy to avoid unnecessary elective neck dissections and to reduce morbidity and mortality from them. We must now pay attention to new imaging techniques such as PET and PET/CT.

摘要

目的

本研究的目的是确定计算机断层扫描(CT)在检测头颈部肿瘤转移性淋巴结方面的预测价值,即其敏感性和特异性。我们还研究了CT在正确进行淋巴结分期方面的能力。

患者与方法

对95例被诊断患有咽和/或喉肿瘤性疾病的患者进行了CT检查。所有患者随后均接受了颈部淋巴结清扫术。在影像学研究中,对于疑似放射学上的淋巴结受累,考虑了以下参数:淋巴结直径大于10mm、病变边缘不清、造影剂注射后包膜强化以及尽管尺寸不大但有中央坏死迹象的淋巴结。

结果

在组织学研究中,70.53%的清扫结果为N+。CT的敏感性为82.09%,特异性为85.71%。CT在67例组织学病理清扫中的55例中检测到阳性,而在28例组织学阴性的清扫中的24例中检测到阴性。加权kappa指数值为0.6408,表明淋巴结正确分期的能力有限。

结论

虽然CT检测头颈部肿瘤转移性淋巴结的能力相当可观,但在正确分期方面则不然。因此,有必要寻找其他能提供更高准确性的影像学检查,以避免不必要的选择性颈部清扫,并降低其发病率和死亡率。我们现在必须关注正电子发射断层显像(PET)和PET/CT等新的成像技术。

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