Park Yoon Hea, Kang Se Hun, Kim Seung Up, Kim Do Young, Park Jun Yong, Ahn Sang Hoon, Han Kwang Hyub, Chon Chae Yoon
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Korean J Gastroenterol. 2011 Sep 25;58(3):149-52. doi: 10.4166/kjg.2011.58.3.149.
Transarterial chemoembolization (TACE) is recommended as one of the first line therapy for unresectable hepatocellular carcinoma (HCC). Rupture of HCC following TACE is a rare and potentially fatal complication. We report a case of hepaticoduodenal fistula with ruptured HCC and liver abscess complicated by TACE. A 52-year-old male was treated by TACE three times, followed by radiation therapy and systemic chemotherapy. 30 days after the last TACE, right upper quadrant pain of abdomen was developed. About 1 month later, computed tomography of abdomen showed ruptured HCC with debris containing liver abscess and hepaticoduodenal fistula. Esophagogastroduodenoscopy revealed hepaticoduodenal fistula and hepatic parenchyme covered with exudate. The patient was managed with supportive care, but the hepaticoduodenal fistula persisted. (Korean J Gastroenterol 2011;58:149-152).
经动脉化疗栓塞术(TACE)被推荐作为不可切除肝细胞癌(HCC)的一线治疗方法之一。TACE术后HCC破裂是一种罕见且可能致命的并发症。我们报告一例经TACE治疗后并发HCC破裂、肝脓肿及肝十二指肠瘘的病例。一名52岁男性接受了3次TACE治疗,随后接受了放射治疗和全身化疗。最后一次TACE治疗30天后,出现右上腹疼痛。大约1个月后,腹部计算机断层扫描显示HCC破裂,伴有含肝脓肿和肝十二指肠瘘的碎片。食管胃十二指肠镜检查发现肝十二指肠瘘及覆盖有渗出物的肝实质。患者接受了支持治疗,但肝十二指肠瘘持续存在。(《韩国胃肠病学杂志》2011年;58:149 - 152)