Ahn Yeon Jeong, Kim Tae Hyo, Moon Sung Won, Choi Su Nyoung, Kim Hyun Jin, Jung Woon Tae, Lee Ok Jae, Ko Gyung Hyuck
Departments of Internal Medicine, Pathology and Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea.
Korean J Gastroenterol. 2011 Sep 25;58(3):153-6. doi: 10.4166/kjg.2011.58.3.153.
Xanthogranulomatous cholecystitis is an unusual inflammatory disease of the gallbladder characterized by severe proliferative fibrosis and the accumulation of lipid-laden macrophages in areas of destructive inflammation. Its macroscopic appearance may occasionally be confused with gallbladder carcinoma. We present a case of perforated xanthogranulomatous cholecystitis presenting as biloma. An 80-year-old woman was referred to our hospital with a 1-week history of abdominal pain and febrile sensation. Abdominal CT showed a biloma in the subhepatic area. The follow-up CT showed that the biloma increased in size. Therefore, ultrasonography-guided aspiration was performed. The aspirated fluid/serum bilirubin ratio was greater than 5, which was strongly suggestive of bile leakage complicated by perforated cholecystitis. She underwent a laparoscopic cholecystectomy with cyst aspiration and adhesiolysis. A histological diagnosis of perforated xanthogranulomatous cholecystitis was made.
黄色肉芽肿性胆囊炎是一种罕见的胆囊炎症性疾病,其特征为严重的增生性纤维化以及在破坏性炎症区域出现充满脂质的巨噬细胞聚集。其大体外观偶尔可能与胆囊癌相混淆。我们报告一例表现为胆汁瘤的穿孔性黄色肉芽肿性胆囊炎病例。一名80岁女性因1周的腹痛和发热感被转诊至我院。腹部CT显示肝下区域有一个胆汁瘤。随访CT显示胆汁瘤大小增加。因此,进行了超声引导下抽吸。抽吸液/血清胆红素比值大于5,强烈提示胆汁漏合并穿孔性胆囊炎。她接受了腹腔镜胆囊切除术、囊肿抽吸术和粘连松解术。作出了穿孔性黄色肉芽肿性胆囊炎的组织学诊断。