80 岁以上先天性冠状动脉瘘患者的性别相关差异：两例报告及文献复习。

Gender-related differences in octogenarians with congenital coronary artery fistula: a report of two cases and a review.

机构信息

Department of Cardiology, ZGT location Hengelo, Hengelo, the Netherlands,

出版信息

Neth Heart J. 2011 Dec;19(12):523-30. doi: 10.1007/s12471-011-0199-9.

DOI:10.1007/s12471-011-0199-9

PMID:21960176

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3221751/

Abstract

AIM

To highlight gender-related differences in octogenarians with a congenital coronary artery fistula (CAF).

MATERIALS AND METHODS

We present two elderly female patients with a congenital fistula, a septuagenarian and a nonagenarian, and review the world literature between 1954-2010.

RESULTS

The septuagenarian patient presented with easy fatigability and the nonagenarian patient with acute myocardial infarction contralaterally to the fistula. Coronary angiography (CAG) demonstrated a coronary-pulmonary artery fistula (CPF). The nonagenarian patient underwent percutaneous coronary intervention of the right coronary artery. CAG revealed a CPF associated with a huge multiple aneurysmal formation. Data from 57 mainly symptomatic patients with a mean age of 75.3 years (range 70-87 years) were collected. The cohort was subdivided into female (mean age 84.3 years) and male (mean age 75.2 years) subgroups and compared with each other. Multi-origin (bilateral and multilateral) was prevalent in females, 40% versus 12% in males. Aneurysmal formation was found in females and males in 40% and 18%, respectively. Ethnicity was 65% Caucasian and 35% Asian. Multi-origin fistulas were prevalent in the Asian (45%) compared with the Caucasian (11%) subset.

CONCLUSIONS

A septuagenarian and a nonagenarian female patient with congenital CAF are presented. On reviewing the literature, important differences were found between elderly females and males with congenital CAF.

摘要

目的

强调 80 岁以上伴有先天性冠状动脉瘘（CAF）患者的性别差异。

材料与方法

我们介绍了 2 例 70 岁和 90 岁的老年女性先天性瘘患者，并回顾了 1954 年至 2010 年期间的世界文献。

结果

70 岁的患者表现为易疲劳，90 岁的患者则表现为瘘侧相反的急性心肌梗死。冠状动脉造影（CAG）显示冠状动脉肺动脉瘘（CPF）。90 岁的患者接受了右冠状动脉经皮冠状动脉介入治疗。CAG 显示 CPF 伴有巨大的多发性动脉瘤形成。收集了 57 例主要表现为症状的患者的数据，平均年龄为 75.3 岁（范围为 70-87 岁）。该队列分为女性（平均年龄 84.3 岁）和男性（平均年龄 75.2 岁）亚组，并进行了相互比较。多起源（双侧和多侧）在女性中更为常见，占 40%，而在男性中仅占 12%。女性和男性的动脉瘤形成分别为 40%和 18%。种族为 65%白种人和 35%亚洲人。多起源瘘在亚洲人群（45%）中比白种人群（11%）更为常见。