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[视黄酸对鸡胚(家鸡)减数分裂的影响]

[The effect of retinoic acid on the meiosis in the chick embryo (Gallus gallus domesticus)].

作者信息

Nekrasova A A, Lukina N A, Kozikova L V, Smirnov A F

出版信息

Tsitologiia. 2011;53(8):659-64.

Abstract

In this study it was shown that the injection of retinoic acid (RA) into incubated eggs on day 9 or 14 induced entry the males germ cells into preleptotene stage of prophase I on day 17, which are absent in the control embryos. At the same time the meiosis marker SCP3 was detected in the germ cells. Which was also absent at control embryos. On day 19 in male embryos the number of male germ cells at the stage preleptoteny increased, but there were no germ cells in the following stages of the prophase of meiosis. In 20-day-old chicks meiotic germ cells were absent. Thus, white it is shown that the influence of RA on the developing chicken embryos induces the entry of germ cells into preleptotene stage of prophase I meiosis. However, further meiotic transformations don't occur. Thus RA is only one of many factors providing meiotic cell division.

摘要

在本研究中发现,在第9天或第14天向孵化的鸡蛋中注射视黄酸(RA)可诱导雄性生殖细胞在第17天进入减数分裂前期的细线前期阶段,而对照胚胎中不存在这种情况。同时,在生殖细胞中检测到减数分裂标记物SCP3,对照胚胎中也不存在该标记物。在雄性胚胎的第19天,细线前期阶段的雄性生殖细胞数量增加,但在减数分裂前期的后续阶段没有生殖细胞。在20日龄雏鸡中不存在减数分裂生殖细胞。因此,虽然已表明RA对发育中的鸡胚胎的影响可诱导生殖细胞进入减数分裂前期I的细线前期阶段。然而,进一步的减数分裂转化并未发生。因此,RA只是众多促进减数分裂细胞分裂的因素之一。

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