[大环内酯类药物的免疫调节作用：在肺病学中可能的临床应用领域]
[Immunomodulating effects of macrolides: areas of possible clinical use in pulmonology].
作者信息
Sinopal'nikov A I
出版信息
Ter Arkh. 2011;83(8):10-20.
PMID:21961326
Abstract
The review is devoted to non-antibacterial effects of macrolides in patients with respiratory diseases: bronchial asthma, bronchoectasis, chronic obstructive pulmonary disease, chronic rhinosinusitis, mucoviscidosis, diffuse bronchiolithiasis, severe flu, posttransplantation obliterating bronchiositis. The discussion covers mechanisms of an immunomodulating action of macrolides. Current data base on non-antibacterial effects of macrolides is analysed.
摘要
本综述致力于探讨大环内酯类药物在呼吸系统疾病患者中的非抗菌作用，这些疾病包括支气管哮喘、支气管扩张症、慢性阻塞性肺疾病、慢性鼻-鼻窦炎、黏液黏稠症、弥漫性支气管结石症、重症流感、移植后闭塞性细支气管炎。讨论涵盖了大环内酯类药物免疫调节作用的机制。分析了关于大环内酯类药物非抗菌作用的现有数据。
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