School of Psychiatry, University of NSW, Sydney, Australia.
Aust N Z J Psychiatry. 2011 Nov;45(11):985-92. doi: 10.3109/00048674.2011.610297. Epub 2011 Oct 2.
The aim of this study was to describe the principal reasons for admission, medical comorbidities, interventions and outcomes of patients admitted to New South Wales hospitals with alcohol-related cognitive impairment.
We extracted data from the NSW Admitted Patient Care Database for nearly 410 000 multi-day hospital admissions from 222 public hospitals ending between July 2006 and June 2007 for people aged 50 and over. Data linkage using a unique patient identifier, derived by the Centre for Health Record Linkage identified hospital transfers and readmissions for individual patients. Using ICD10-AM codes, we identified patients with alcohol-related dementia, amnesic syndrome due to alcohol, and Wernicke's encephalopathy, their principal reasons for admission and medical comorbidities, and procedures undertaken. Outcomes were length of stay, mortality, discharge destination, and readmission.
A total of 462 patients diagnosed with alcohol-related dementia (n = 300; 82% male, mean age 63.9 years), Wernicke's encephalopathy (n = 77) or amnesic syndrome due to alcohol (n = 126) were identified with overlap between diagnoses. Alcohol-related dementia occurred in 1.4% of dementia patients, and was more likely to occur in younger age groups and men than other types of dementia. Alcohol-related mental disorder was recorded in 70% of alcohol-related dementia multi-day admissions: dependence (52%), 'harmful use' (11%) and withdrawal (12%). Principal reasons for admission for multi-day stays included alcohol-related mental disorder (18%), liver disease (11%) and injuries/poisonings (10%). Medical comorbidity was common. Like other dementia patients, alcohol-related dementia patients had longer length of stay (mean of 15 days) than non-dementia patients and more transfers to residential care (7%). However, mortality was similar to non-dementia patients (5%). Discharge at own risk was high (3.7%).
Alcohol-related dementia is a preventable and potentially reversible condition. Investigation of intervention strategies initiated during hospitalization are warranted.
本研究旨在描述因酒精相关认知障碍而住院的患者的主要入院原因、合并症、干预措施和结局。
我们从新南威尔士州住院患者护理数据库中提取了 2006 年 7 月至 2007 年 6 月期间,222 家公立医院近 410000 例住院 1 天以上的患者数据。通过健康记录链接中心提供的唯一患者标识符进行数据链接,可确定每位患者的院内转科和再入院情况。我们使用国际疾病分类第 10 版修订本(ICD10-AM)编码确定酒精相关痴呆、酒精所致遗忘综合征和韦尼克脑病患者,以及他们的主要入院原因和合并症,以及所进行的操作。结局包括住院时间、死亡率、出院去向和再入院。
共确定了 462 例诊断为酒精相关痴呆(n = 300;82%为男性,平均年龄 63.9 岁)、韦尼克脑病(n = 77)或酒精所致遗忘综合征(n = 126)的患者,这些患者的诊断存在重叠。酒精相关痴呆占痴呆患者的 1.4%,且比其他类型的痴呆更易发生在年轻年龄段和男性中。酒精相关精神障碍在酒精相关痴呆的 1 天以上住院患者中占 70%:依赖(52%)、“有害使用”(11%)和戒断(12%)。多日住院的主要入院原因包括酒精相关精神障碍(18%)、肝脏疾病(11%)和损伤/中毒(10%)。合并症很常见。与其他痴呆患者一样,酒精相关痴呆患者的住院时间(平均 15 天)比非痴呆患者长,且更倾向于转至养老院(7%)。然而,死亡率与非痴呆患者相似(5%)。自行出院风险较高(3.7%)。
酒精相关痴呆是一种可预防和潜在可逆转的疾病。有必要研究在住院期间开始的干预策略。