Dow Wolff Cellulosics, The Dow Chemical Company, Midland, MI, USA.
Drug Dev Ind Pharm. 2012 May;38(5):521-39. doi: 10.3109/03639045.2011.616512. Epub 2011 Oct 1.
This three-part review has been developed following the evaluation of literature where ethylcellulose, methylcellulose, or hypromellose was used to make microcapsules. Parts 1 and 2 of the review are published in separate papers. Part 1 covers the various materials used to formulate microcapsules, and Part 2 covers the various techniques used to make microcapsules. In the current paper, Part 3 covers the end-use applications for which microcapsules are used. Examples of applications to be covered include modified release, improved efficacy and safety, multiparticulate compression, improved processability and stability, and taste- and odor-masking. It is hoped that formulators can use Part 3 to understand the various end-use applications of microcapsules made from these encapsulating polymers. SciFinder was utilized to perform the literature search. SciFinder leverages literature databases, such as Chemical Abstracts Service Registry and Medline. A total of 379 references were identified during the review. The need for a three-part review reflects the extensive amount of literature identified concerning these three encapsulating polymers.
本综述分为三部分，是在评估使用乙基纤维素、甲基纤维素或羟丙甲纤维素制造微胶囊的文献后编写的。综述的第 1 部分和第 2 部分分别发表在两篇论文中。第 1 部分涵盖了用于制备微胶囊的各种材料，第 2 部分涵盖了用于制备微胶囊的各种技术。在当前的论文中，第 3 部分涵盖了微胶囊的最终用途应用。将涵盖的应用示例包括控释、提高疗效和安全性、多颗粒压缩、改善加工和稳定性，以及掩味和掩臭。希望配方师可以使用第 3 部分来了解这些包封聚合物制成的微胶囊的各种最终用途应用。SciFinder 用于执行文献检索。SciFinder 利用了文献数据库，例如化学文摘服务登记处和 Medline。在综述过程中共确定了 379 篇参考文献。之所以需要三部分综述，是因为涉及这三种包封聚合物的文献数量非常庞大。
