State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Talanta. 2011 Oct 15;85(5):2451-7. doi: 10.1016/j.talanta.2011.07.106. Epub 2011 Aug 9.
A porous polysulfone microcapsule containing organic modified montmorillonite and magnetic nanoparticles (OMMT-Fe(3)O(4)@PSF) has been successfully prepared by a phase-inversion method and evaluated as a magnetic solid-phase extraction (MSPE) sorbent for clean-up and enrichment of 4-chlorophenol (4-CP) and 2-chlorophenol (2-CP) in aqueous samples. Compared with a microcapsule containing the conventional extraction sorbent C18 (C18-Fe(3)O(4)@PSF), OMMT-Fe(3)O(4)@PSF had much lower cost, a faster adsorption rate, and superior uptake amounts for the investigated analytes. The proposed microcapsule has been developed for the extraction of 4-CP and 2-CP from environmental water samples and their analysis by high-performance liquid chromatography with UV detection (HPLC-UV). Various parameters, such as pH, extraction time, the mass of sorbent, and the desorption conditions, have been evaluated and the calibration curves of the chlorophenols were linear (R(2) ≥ 0.9985) in the range from 1.01 to 104.5 ng mL(-1). The limits of detection at a signal-to-noise (S/N) ratio of 3 were 0.22 and 0.17 ng mL(-1) and the limits of quantification calculated at S/N=10 were 1.52 and 1.07 ng mL(-1) for 2-CP and 4-CP, respectively. The recoveries of 2-CP and 4-CP from natural water and the treated wastewater samples were in the range of 84.4-115% with relative standard deviations (RSDs) lower than 7.0%. The results have demonstrated the suitability of the MSPE approach for the analysis of trace chlorophenols in aqueous samples.
一种含有有机改性蒙脱石和磁性纳米粒子的多孔聚砜微胶囊（OMMT-Fe(3)O(4)@PSF）已成功通过相转化法制备，并作为磁性固相萃取（MSPE）吸附剂用于水样中 4-氯苯酚（4-CP）和 2-氯苯酚（2-CP）的净化和富集。与含有传统萃取吸附剂 C18 的微胶囊（C18-Fe(3)O(4)@PSF）相比，OMMT-Fe(3)O(4)@PSF 具有更低的成本、更快的吸附速率和对被分析物更高的吸附量。该微胶囊已被开发用于从环境水样中提取 4-CP 和 2-CP，并通过高效液相色谱法与紫外检测（HPLC-UV）进行分析。已经评估了各种参数，例如 pH、萃取时间、吸附剂的质量和洗脱条件，并且氯酚的校准曲线在 1.01 至 104.5ng mL(-1) 的范围内呈线性（R(2)≥0.9985）。在信噪比（S/N）为 3 时，氯酚的检出限分别为 0.22 和 0.17ng mL(-1)，而在 S/N=10 时，氯酚的定量限分别为 1.52 和 1.07ng mL(-1)。2-CP 和 4-CP 从天然水和处理后的废水样品中的回收率在 84.4-115%范围内，相对标准偏差（RSD）低于 7.0%。结果表明，MSPE 方法适用于水样中痕量氯酚的分析。
