Department of Internal Medicine III, Friedrich-Schiller-University Jena, Erlanger Allee 101, 07747 Jena, Germany.
Joint Bone Spine. 2012 Jul;79(4):384-8. doi: 10.1016/j.jbspin.2011.07.011. Epub 2011 Oct 2.
Computer-aided joint space analysis (CAJSA) is a recently developed, semi-automated tool to aid in the measurement of joint space margins based on hand radiographs. The objective of this study is to verify the potential effect of hand rotation during X-ray imaging on the measurement of joint space width using CAJSA and to evaluate the reproducibility of the CAJSA technique in healthy subjects and in patients with rheumatoid arthritis.
All joint space distance (JSD) measurements were performed using CAJSA-technology at the metacarpophalangeal articulation based on conventional and digital hand radiographs.
I. Hand rotation showed an effect on the reproducibility with CV ranging between 0.39% (angulation 1°) and 1.66% (angulation 19°). II. Regarding the overall reproducibility of the CAJSA method, the intra-radiograph reproducibility of JSD was calculated with CV=0.54% for conventional images and CV=0.38% for digital images. The inter-radiograph reproducibility error was observed with CV=0.66% (conventional images) and CV=0.63% (digital images). III. The study revealed a reproducibility for CAJSA measurements in RA ranging between 0.37% (JSD-MCP ring finger; van der Heijde-modification of the Sharp method score 1) to 1.37% (JSD-MCP index finger; van der Heijde-modification of the Sharp method score 3).
CAJSA measures JSD at the metacarpophalangeal articulation with high reproducibility in healthy subjects and in patients with differing stages of rheumatoid arthritis. Additional findings show that hand rotation during X-ray imaging has an impact on the CAJSA measurements; thus avoiding acquisition of hand radiographs with a rotation error of more than 15 degrees can be recommended.
计算机辅助关节间隙分析（CAJSA）是一种最近开发的半自动工具，用于辅助基于手部 X 光片测量关节间隙边缘。本研究的目的是验证手部旋转在 X 射线成像过程中对手指关节间隙宽度测量的潜在影响，并评估 CAJSA 技术在健康受试者和类风湿关节炎患者中的可重复性。
所有关节间隙距离（JSD）测量均在手掌指关节处使用 CAJSA 技术在常规和数字手部 X 光片上进行。
I. 手部旋转对手的可重复性有影响，CV 范围为 0.39%（角度 1°）至 1.66%（角度 19°）。II. 就 CAJSA 方法的整体可重复性而言，JSD 的内照片可重复性计算为常规图像的 CV=0.54%和数字图像的 CV=0.38%。放射照片之间的可重复性误差观察到 CV=0.66%（常规图像）和 CV=0.63%（数字图像）。III. 研究表明，CAJSA 在 RA 中的测量具有可重复性，范围为 0.37%（JSD-MCP 环指；van der Heijde-Sharp 方法评分 1 的改良）至 1.37%（JSD-MCP 食指；van der Heijde-Sharp 方法评分 3 的改良）。
CAJSA 在手掌指关节处测量 JSD，在健康受试者和不同阶段的类风湿关节炎患者中具有高度的可重复性。进一步的发现表明，手部旋转在 X 射线成像过程中对 CAJSA 测量有影响；因此，可以推荐避免手部 X 光片的采集旋转误差超过 15 度。
