Glieca F, Santarelli P, Luciani N, La Rovere G, Battaglini G, Stoduto L, Antico A, Bellisario A, Colamussi G, Calafiore A M
Istituto di Clinica Cardiovascolare, Università degli Studi, G. D'Annunizo Chieti.
Minerva Cardioangiol. 1990 Apr;38(4):135-40.
The aim of this work was to identify the best treatment available for massive pulmonary thromboembolism which still remains a frequent and sometimes lethal complication for surgical and non-surgical patients. The Authors underline the difficulties of diagnosis and the need for therapy at the earliest possible stage. At present, clinical management involves the use of: anticoagulants, thrombolytic agents and surgical embolectomy. In conclusion, the authors state that pulmonary thromboembolism, even when massive, has been transformed into a medically interesting pathology which can be cured using heparin and thrombolytic agents. However, surgical treatment is mandatory when patients reveal adverse effects to drug therapy, when medical therapy is insuccessful, or when patients are seriously ill with recurrent cardiac arrest.
这项工作的目的是确定针对大面积肺血栓栓塞症的最佳可用治疗方法，大面积肺血栓栓塞症对于手术和非手术患者而言仍是一种常见且有时致命的并发症。作者强调了诊断的困难以及尽早进行治疗的必要性。目前，临床管理涉及使用：抗凝剂、溶栓剂和手术取栓术。总之，作者指出，肺血栓栓塞症即使是大面积的，也已转变为一种在医学上值得关注的可通过肝素和溶栓剂治愈的病症。然而，当患者出现药物治疗不良反应、药物治疗无效或患者病情严重且反复心脏骤停时，手术治疗是必要的。
