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Human recombinant interleukin-2 as an experimental therapeutic.

作者信息

Winkelhake J L, Gauny S S

机构信息

Department of Pharmacology, Cetus Corporation, Emeryville, California 94608.

出版信息

Pharmacol Rev. 1990 Mar;42(1):1-28.

PMID:2196590
Abstract
摘要

相似文献

1
Human recombinant interleukin-2 as an experimental therapeutic.
Pharmacol Rev. 1990 Mar;42(1):1-28.
2
Rationale and therapeutic basis for patients receiving recombinant interleukin-2.接受重组白细胞介素-2治疗的患者的理论基础和治疗依据。
Semin Oncol Nurs. 1993 Aug;9(3 Suppl 1):3-7.
3
[Pharmacologic studies with recombinant human interleukin 2].
Zentralbl Veterinarmed A. 1987 Dec;34(10):755-65.
4
[Interleukin-2 and cancer immunotherapy].[白细胞介素-2与癌症免疫疗法]
Vopr Onkol. 1989;35(2):141-50.
5
[Interleukin 2].[白细胞介素2]
Ter Arkh. 1988;60(5):42-6.
6
Adoptive immunotherapy of cancer using lymphokine activated killer cells and recombinant interleukin-2.利用淋巴因子激活的杀伤细胞和重组白细胞介素-2进行癌症的过继性免疫治疗。
Important Adv Oncol. 1986:55-91.
7
Systematic preclinical study on the therapeutic properties of recombinant human interleukin 2 for the treatment of metastatic disease.重组人白细胞介素2治疗转移性疾病的治疗特性的系统临床前研究。
Cancer Res. 1987 Nov 1;47(21):5725-32.
8
In vivo and in vitro activation of NK cytotoxicity with IL-2.利用白细胞介素-2在体内和体外激活自然杀伤细胞的细胞毒性。
Prog Clin Biol Res. 1987;244:275-85.
9
Future directions for recombinant interleukin-2 in cancer: a chronic inflammatory disorder.重组白细胞介素-2在癌症（一种慢性炎症性疾病）中的未来发展方向
Cancer J Sci Am. 1997 Dec;3 Suppl 1:S106-8.
10
[Biological immunomodulators in the treatment of cancer].[生物免疫调节剂在癌症治疗中的应用]
Sangre (Barc). 1988 Apr;33(2):132-43.

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Decreased response rates by the combination of histamine and IL-2 in melphalan-based isolated limb perfusion.在基于美法仑的离体肢体灌注中，组胺与白细胞介素-2联合使用时反应率降低。
Cancer Immunol Immunother. 2007 Apr;56(4):573-80. doi: 10.1007/s00262-006-0206-y. Epub 2006 Aug 1.
6
Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy.靶向白细胞介素-2治疗后小鼠体内持久且可转移的肿瘤免疫
J Clin Invest. 1996 Dec 15;98(12):2801-4. doi: 10.1172/JCI119107.
7
Interleukin-2-containing liposomes: interaction of interleukin-2 with liposomal bilayers and preliminary studies on application in cancer vaccines.含白细胞介素-2的脂质体：白细胞介素-2与脂质体双层膜的相互作用及在癌症疫苗中的应用初步研究
Pharm Res. 1993 Dec;10(12):1715-21. doi: 10.1023/a:1018913912580.
8
Local anaesthetic-like effect of interleukin-2 on muscular Na+ channels: no evidence for involvement of the IL-2 receptor.
Pflugers Arch. 1994 Jan;426(1-2):61-7. doi: 10.1007/BF00374671.
9
Persistent augmentation of natural-killer- and T-cell-mediated cytotoxicity in peripheral blood mononuclear cells pulsed in vitro with high-dose recombinant interleukin-2 prior to culturing with a low maintenance dose.在用低维持剂量培养之前，用高剂量重组白细胞介素-2体外脉冲处理外周血单个核细胞后，自然杀伤细胞和T细胞介导的细胞毒性持续增强。
Cancer Immunol Immunother. 1994 Jul;39(1):34-40. doi: 10.1007/BF01517178.
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Interleukin-2. A review of its pharmacological properties and therapeutic use in patients with cancer.白细胞介素-2。其药理学特性及在癌症患者中的治疗应用综述。
Drugs. 1993 Sep;46(3):446-514. doi: 10.2165/00003495-199346030-00009.