Olusina Db, Ezemba N, Nzegwu M A
Department of Morbid Anatomy, University of Nigeria Teaching Hospital, Enugu.
Niger Med J. 2011 Jan;52(1):60-63.
Lymphomatoid granulomatosis (LYG) is a rare angiocentric lymphoproliferative process predominantly affecting the lung. The diagnosis of this condition is often difficult as the physical signs, history, chest x-ray, and routine laboratory investigations are usually non-specific. Nevertheless, it is important to establish a tissue diagnosis, as this lymphoproliferative disorder can be refractory to treatment and even progress to overt lymphoma. We report a case of pulmonary LYG in a 52-year old Nigerian man of Ibo extraction treated in our centre in 2001 and followed up for a year. The difficulty in making diagnosis is highlighted and treatment modality discussed.
淋巴瘤样肉芽肿病(LYG)是一种罕见的主要累及肺部的血管中心性淋巴增殖性病变。由于体格检查体征、病史、胸部X线检查及常规实验室检查通常无特异性,因此该病的诊断往往很困难。然而,确立组织学诊断很重要,因为这种淋巴增殖性疾病可能对治疗耐药,甚至进展为明显的淋巴瘤。我们报告一例2001年在我们中心接受治疗并随访一年的52岁伊博族尼日利亚男性的肺部LYG病例。强调了诊断的困难并讨论了治疗方式。