Division of Urologic Oncology, Department of Urology, New York University Langone Medical Center, New York, NY, USA.
Ther Adv Urol. 2011 Aug;3(4):183-92. doi: 10.1177/1756287211418724.
Prostate cancer treatment is a controversial topic amongst physicians and patients alike. Radical therapies such as prostatectomy and whole gland radiation offer the best outcomes in terms of oncologic efficacy, but the decision to undergo treatment must be weighed against its potential morbidity. Over the past decade, the concept of focal therapy for prostate cancer has been introduced as a potential method of achieving oncologic control with a lesser degree of morbidity. Focal therapy refers to isolated ablation of a tumor focus with sparing of uninvolved, surrounding tissue. While it remains in the early stages of development, considerable research is underway that will help determine the optimal method of achieving this goal. Current areas of investigation include appropriate candidate selection, lesion identification, modality of treatment, and follow-up strategies.
前列腺癌的治疗是医生和患者都非常关注的一个话题。根治性治疗如前列腺切除术和全腺体放疗在肿瘤疗效方面提供了最佳的结果，但必须权衡治疗的潜在发病率。在过去的十年中，前列腺癌的局部治疗概念已经被引入，作为一种在发病率较低的情况下实现肿瘤控制的潜在方法。局部治疗是指孤立地消融肿瘤病灶，同时保留未受影响的周围组织。虽然它仍处于发展的早期阶段，但正在进行大量的研究，这将有助于确定实现这一目标的最佳方法。目前的研究领域包括合适的候选者选择、病灶识别、治疗方式和随访策略。
