Division of Respiratory, Critical Care and Sleep Medicine, University of Saskatchewan, Saskatoon, Saskatchewan.
Can Respir J. 2011 Sep-Oct;18(5):271-4. doi: 10.1155/2011/408091.
To compare a commercially available, level III in-home diagnostic sleep test (Embletta, Embletta USA) and in-laboratory polysomnography (PSG) in women with suspected obstructive sleep apnea (OSA).
Consecutive women scheduled for routine PSG testing for evaluation of clinically suspected OSA and who met inclusion⁄exclusion criteria, were invited to participate. An in-home Embletta portable monitor test was performed one week before or after diagnostic PSG.
Forty-seven of 96 women who met the inclusion⁄exclusion criteria agreed to participate. The mean (± SD) age of the patients was 52.0 ± 11.0 years, with a mean body mass index of 34.86 ± 9.04 kg⁄m2, and 66% (31 of 47) of patients were at high risk for OSA according to the Berlin score. Paired analysis of the overall population revealed no significant difference in mean apnea⁄hypopnea index (AHI) between the two diagnostic methods (P = 0.475). At an AHI of ≥ 5, the Embletta test was highly sensitive (90.6%) in determining abnormal versus normal OSA, with a positive predictive value of 82.7%. However, a higher Embletta AHI threshold of ≥ 10 may be more useful, with a higher level of agreement (kappa coefficient) with PSG testing and a positive predictive value of 92.3%. The in-home study was less useful at distinguishing severe from nonsevere OSA, yielding a sensitivity of 50%.
In women believed to be at high-risk for OSA, Embletta in-home sleep testing is useful for the detection of sleep disordered breathing.
比较一种市售的、三级家庭诊断睡眠测试（Embletta，Embletta USA）和实验室多导睡眠图（PSG）在疑似阻塞性睡眠呼吸暂停（OSA）女性中的应用。
连续邀请符合纳入/排除标准、计划接受常规 PSG 测试以评估临床疑似 OSA 的女性参与研究。在诊断性 PSG 前或后一周内进行家庭式 Embletta 便携式监测仪测试。
符合纳入/排除标准的 96 名女性中有 47 名同意参与。患者的平均（±SD）年龄为 52.0±11.0 岁，平均体重指数为 34.86±9.04kg/m2，根据柏林评分，66%（31 名/47 名）的患者有发生 OSA 的高风险。对总体人群进行配对分析显示，两种诊断方法的平均呼吸暂停/低通气指数（AHI）无显著差异（P=0.475）。在 AHI≥5 时，Embletta 测试在确定异常与正常 OSA 方面具有高度敏感性（90.6%），阳性预测值为 82.7%。然而，更高的 Embletta AHI 阈值（≥10）可能更有用，与 PSG 测试的一致性（kappa 系数）更高，阳性预测值为 92.3%。家庭研究在区分严重与非严重 OSA 方面效果较差，敏感性为 50%。
在被认为有发生 OSA 高风险的女性中，Embletta 家庭睡眠测试可用于检测睡眠呼吸障碍。
