Shipton E A
Department of Anaesthesia, University of Otago, Christchurch, New Zealand.
Anaesth Intensive Care. 2011 Sep;39(5):824-36. doi: 10.1177/0310057X1103900506.
All chronic pain was once acute, but not all acute pain becomes chronic. The transition of acute postoperative pain to chronic post surgical pain is a complex and poorly understood developmental process. The manuscript describes the various factors associated with the transition from acute to chronic pain. The preoperative, intraoperative and postoperative surgical, psychosocial, socio-environmental and patient-related factors and the mechanisms involved are discussed and preventive (or limitation) strategies are suggested. In future, the increasing understanding of genetic factors and the transitional mechanisms involved may reveal important clues to predict which patients will go on to develop chronic pain. This may assist the development of appropriate interventions affecting not only the individual concerned, but also ultimately the community at large.
所有慢性疼痛都曾是急性疼痛，但并非所有急性疼痛都会转变为慢性疼痛。急性术后疼痛向慢性术后疼痛的转变是一个复杂且了解甚少的发展过程。本文描述了与从急性疼痛转变为慢性疼痛相关的各种因素。文中讨论了术前、术中和术后的手术、心理社会、社会环境及患者相关因素以及其中涉及的机制，并提出了预防（或限制）策略。未来，对遗传因素及相关转变机制的深入了解可能会揭示重要线索，以预测哪些患者会发展为慢性疼痛。这不仅有助于为相关个体制定合适的干预措施，最终也将惠及整个社会。
