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提高麻疹、腮腺炎、风疹疫苗接种率:群体免疫是一个现实目标。

Improving MMR vaccination rates: herd immunity is a realistic goal.

机构信息

St Stephen's Health Centre, London E3 5ED, UK.

出版信息

BMJ. 2011 Oct 4;343:d5703. doi: 10.1136/bmj.d5703.

Abstract

PROBLEM

As measles is a highly infectious disease, the United Kingdom recommendation is for at least 95% of children to receive a first vaccination with the measles, mumps, and rubella (MMR) vaccine before age 2 years and a booster before age 5 years to achieve herd immunity and prevent outbreaks. Reported vaccination rates for England have improved since a low level in 2003-4. Coverage for London is consistently lower than for England, however, and concerns have been expressed that there could be an epidemic of measles in the capital.

DESIGN

Observational time series study.

SETTING

London Borough of Tower Hamlets. Key measurements for improvement Uptake rates for childhood vaccinations. The key target was to reach 95% coverage for the first MMR vaccine before age 2 years.

STRATEGIES FOR CHANGE

Financial support for the development of geographically based networks of general practices. Commissioning of care packages, incentivising delivery of high quality integrated care with network level vaccination targets of 95%. Innovative use of information technology to enable robust call and recall processes, active follow-up of defaulters, and increased knowledge about the demography of the children most difficult to reach.

EFFECTS OF CHANGE

The development of networks of practices facilitated collaborative working among primary care clinicians and other stakeholders; peer review of achievements; and an element of healthy competition. Uptake improved for all childhood vaccinations, and to herd immunity levels for most. Uptake of the first MMR vaccine before age 2 years rose from 80% in September 2009 to 94% in March 2011.

LESSONS LEARNT

Achieving herd immunity for childhood vaccinations is an achievable target in an ethnically mixed, socially deprived inner city borough. The ability to identify characteristics of the difficult to reach groups, including significant differences in uptake across different ethnicities, will allow targeted interventions that may further improve overall coverage.

摘要

问题

由于麻疹是一种高度传染性疾病,因此英国的建议是,至少 95%的儿童在 2 岁之前接种麻疹、腮腺炎和风疹(MMR)疫苗,在 5 岁之前接种加强针,以实现群体免疫并预防疫情爆发。自 2003-2004 年的低水平以来,英格兰的疫苗接种率有所提高。然而,伦敦的疫苗接种覆盖率始终低于英格兰,并且有人担心首都可能会爆发麻疹疫情。

设计

观察时间序列研究。

地点

伦敦塔哈姆雷特自治市。

改进措施

儿童疫苗接种率。主要目标是在 2 岁之前达到 95%的首剂 MMR 疫苗覆盖率。

变革策略

为发展以地理位置为基础的全科医生网络提供财政支持。制定护理套餐,激励提供高质量的综合护理,并设定网络层面 95%的疫苗接种目标。创新使用信息技术,实现强大的呼叫和召回流程,积极跟踪违约者,并增加对最难接触到的儿童的人口统计数据的了解。

变革效果

实践网络的发展促进了初级保健临床医生和其他利益相关者之间的协作工作;成就的同行审查;以及健康竞争的元素。所有儿童疫苗的接种率都有所提高,大多数疫苗的接种率都达到了群体免疫水平。首剂 MMR 疫苗在 2 岁之前的接种率从 2009 年 9 月的 80%上升到 2011 年 3 月的 94%。

经验教训

在种族混合、社会贫困的市中心自治市实现儿童疫苗接种群体免疫是一个可行的目标。能够识别难以接触到的群体的特征,包括不同种族之间接种率的显著差异,将允许采取有针对性的干预措施,进一步提高整体覆盖率。

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